Plexus Slim is a weight loss and blood sugar lowering supplement that has become quite popular over the last few years. In fact, it's so popular that my original review of the product has over 1000 comments. Since writing my original review, several have told me that Plexus Slim has a new formula. As such, I feel this product deserves another look. The main goal of this review is to compare the old plexus Slim formula to the new formula and see if anything has changed. I'll also cover the research on Plexus Slim. For additional info, see my original plexus Slim review and my review of the Plexus Accelerator Plus supplement, as well as my reviews of Plexus Boost and Plexus ProBio5.
Plexus Slim Formulas: New vs. Old
Below is side by side comparison of the new Plexus Slim formula to the old formula.
|Chromium Nicotinate 200 mcg (167%)|
|Proprietary Blend||Proprietary Blend|
|Chlorogenic acid||Chlorogenic acid|
|Garcinia cambogia||Citrin K|
|Alpha lipoic acid||Alpha lipoic acid|
|Hoodia gordonii (now removed)||Oxypregnane steroidal glycoside|
|Chromium (amino nicotinate GTF)|
|Other Ingredients||Other ingredients|
|Citric acid||Citric acid|
|Natural flavors||Natural flavors|
|Beet root extract||Beet root extract|
|Stevia||Grape skin extract|
|Luo han guo||Stevia|
|Lo han extract|
The plexus slim website states that the product is has no caffeine or MSG or stimulants. They also say it's vegan and gluten free.
What's Different In The New Formula
Comparing both old and new formulas these are the differences that I see.
1. Chromium has moved positions. It used to be the last ingredient in the proprietary blend. It appears at the very top of the ingredients list.
This may mean the new Plexus Slim formula has more chromium than it originally had. They also now tell us how much chromium Plexus Slim contains (200 micrograms). Here is my review of chromium and weight loss.
2. Both the old and new formula contain chromium nicotinate. This is a complex of both chromium and niacin. Chromium is often touted for its ability to help reduce blood sugar levels and while there is some evidence of this, not all studies find it works. For example, in this 2013 study chromium nicotinate did not help people with type 2 diabetes.
3. Most of the ingredients in the new Plexus Slim formula are the same as in the old formula, except that several ingredients now have more familiar names. For example, I noticed these similarities:
A. In the old formula, hoodia was given the overly complicated name, oxypregnane steroidal glycoside. Now, they call it hoodia gordonii.
Update: After I wrote this review I was told that hoodia is no longer in Plexus Slim.
B. The old formula contained “Citrin K” which is another name for garcinia cambogia. Now they call it garcinia cambogia. See my review of Garcinia cambogia and weight loss for additional information.
C. The old formula contained “lo han” as a sweetener. The new formula has “Luo han guo” which is the same thing as lo han. Even some pages of the Plexus Slim website still call it “lo han.” Here is a review of Luo han guo at drugs.com for more info.
D. In the old formula, chromium was called “amino nicotinate” and now it's called chromium nicotinate They are the same thing.
4. They have removed grape skin extract from the new formula. I'm not sure if this makes a significant difference or not in how effective Plexus Slim might be. I was told this was because people were having allergic reactions to this ingredient.
There are a lot of ingredients in Plexus Slim but since they have not really changed the formula, I'll direct people to my original plexus slim review for a run down on the studies on each of the ingredients.
Summary: Changes To New Formula
- Chromium is the first ingredient listed
- We are told how much chromium is in the new formula
- Grape skin extract is removed
- Same ingredients. New names
- Hoodia is removed from formula
Question for Ambassadors: why was grape seed extract and hoodia removed from plexus slim?
Who Makes Plexus Slim?
Plexus Slim World Wide Inc. is the maker of Plexus Slim as well as other Plexus Slim supplements. The company is located at 15649 North Greenway Hayden Loop Scottsdale, AZ 85260. This is a different address than when I originally reviewed the product. According to the Better Business Bureau, the company was created in 2005. The BBB gives Plexus World Wide a rating of B + as of November 2013. Check the link for updates as ratings sometimes change.
When I originally reviewed this product, the company had a rating of A+. This is likely to happen to any company that has been around for more than a few years because you can't please everybody. To contact Plexus Slim Worldwide, call their contact number : 480- 998-3490.
Plexus Slim Research
I searched ClincalTrials.gov to see if there were any studies being conducted on Plexus Slim but didn’t see any. I also searched the National Library of Medicine for “Plexus Slim” but likewise saw nothing. This says to me that the product has no published peer reviewed research and that there appears to be none in the pipeline either.
Plexus Slim Ambassadors often tell me that the product was originally was studied ―not for weight loss―but rather for its effects on reducing blood sugar. As proof of this, they mention a clinical trial done on 8 people with type 2 diabetes conducted between June and October 2008.
The results of this study can be seen on the Science page of PlexusWorldWide.com. While the study does not appear to be peer reviewed, it does seem to show that people taking plexus slim had reduced blood sugar and body weight. When looking at the summary of this trial on the PS website, a few things occurred to me:
1. The study refers to these 8 people as “patients.” This makes me wonder if the people were confined to a hospital or clinic? If yes, this is not a real life test of plexus slim because most people won't be monitored for food intake the way people in hospitals /clinics likely are. If anyone can answer this question, I'd appreciate it.
2. The study only had 8 people. That’s not a lot of people.
3. The study doesn’t seem to be peer reviewed / published (If I am wrong let me know where the study is published and I will update this review)
Another issue is that the clinical study used the original plexus slim formula. Since the formula has been tweaked a little bit ( i.e., removal of grape seed extract and hoodia), there will be those who will say the results of the clinical trial can't be extrapolated to the new formula.
Regardless as to whether the product was originally studied for its effects on blood sugar, there is no doubt that Plexus Slim is marked mostly for weight loss. As proof of this, here are the first 4 sentences used to describe the product on the product's website”
” Having trouble losing weight and keeping it off? You're not alone. But don't worry! Finally there is an all-natural, healthy solution to help you lose weight for the long term.”
Notice, there is no mention of blood sugar, only weight loss. In fact, in the list of Features and Benefits for the product, blood sugar is listed as #2. Weight loss is listed as the #1 benefit.
That said, if plexus slim helps weight loss (by getting people to eat less calories), then I'd expect blood sugar to be reduced also.
Does The New Formula Work?
In my opinion, the new Plexus Slim formula isn't significantly different than the old formula. For the most part, it just looks like they changed the names of ingredients and, maybe added some more chromium. Therefore, if the old formula helped people lose weight (some say it works while others say it doesn't ) then I think the new formula should have basically the same effects. That said, if you read the comments, you will see some people who say the new Plexus formula does not work the same way as the old formula.
Interestingly, when people report to their ambassadors that Plexus Slim doesn't work, it appears some ambassadors blame the person- rather than Plexus Slim. Some are commenting that when the new formula doesn't work that ambassadors try to sell them the Plexus probiotic supplement.
Its worth noting that neither new or old formula appears to have any published peer reviewed evidence, and that’s too bad ,considering the popularity of this product. Also see my review of Plexus Boost for more info.
What do you think?