Have you seen the TV commercials for Lipozene, featuring Holly Robinson Peete and Rodney Peete? Maybe you've seen the commercials and wondered if Lipozene really worked?Lipozene has been around a long time and was actually one of the first supplements I looked at when this site was created. It was time to take a new look at this diet supplement to see if anything has changed. In this review, we will look at the ingredients in Lipozene, its evidence and side effects and help you see if this weight loss supplement is right for you. See the review of Metamucil and weight loss for more information.
Does Lipozene have any clinical studies that prove it really works? Well, on the FAQ page of Lipozene.com, there is a question titled “What were Lipozene's Clinical Study results?” The answer to that question makes reference to a company sponsored study that showed those taking the supplement for 8 weeks “lost 4.93 more pounds than the placebo group, and 3.86 lbs. of body fat!”
That's pretty impressive, but what they don't tell us is if the study was published in a medical journal. If it was, then we could see
- How many people were in the study?
- Was there a placebo group?
- Were there any side effects?
To further clarify this issue, I searched both ClinicalTrials.gov and Pubmed.gov for research. I simply went to those sites and entered “Lipozene.”
No relevant studies showed up.
Failure to locate the study may just mean it was not submitted to medical research journals. While I like to see research that is published (so I can see what the study was all about, not just the results), this is not a deal breaker in this instance because I'm very familiar with the ingredient in Lipozene.
Let's look at that next.
The label on the bottle tells us that 2 capsules of Lipozene contains 1500 mg of a single ingredient. That ingredient is called:
- Amorphophallus Konjac
This is the name of a large, purple colored plant that is common to various parts of Asia. The root of the plant is often where the ingredients in supplements comes from . Thus, another name for this on supplement labels is konjac root extract. Other names include glucomannan, devils tongue and simply, konjac.
By whatever name you call it by, it's a water soluble fiber that expands in size -like a sponge – when it comes in contact with a liquid. This ability to expand, temporarily stretches the stomach, slowing gastric emptying (stomach emptying) making our brain think that we are full.
This in turn, reduces our desire to eat. This is the way that Lipozene and other konjac fiber supplements work.
Other weight loss supplements contained this konjac root extract include:
See those reviews for more info on those products.
Other Ingredients In Lipozene
The product label also tells us that Lipozene also contains
My guess is hydroxy-methyl-cellulose is what makes up the capsules. As for leucine, I'm not why it's present. Leucine is one of the branch chain amino acids (BCAAs). It's popular in bodybuilder supplements because it seems to promote muscle growth.
That said, I don't think that is why leucine is in Lipozene. I tried to call Obesity Research Institute, the company that makes Lipozene but was unable to reach a human. See the Contact section below for more on my difficulties.
Let's now review some of the research on konjac fiber and see what we can make of it.
Konjac Fiber Research
There is research on konjac fiber and weight loss. Remember the other name for this fiber is glucomannan. On the product package, it's called “Amorphophallus Konjac.”
In a 2015 study, 83 overweight men and women were given either konjac supplements or a placebo for 60 days. The amount of konjac used was 3000 mg (3 grams) a day. These researchers noted that the konjac supplements caused significantly more weight and fat loss than those who took the placebo.
In a review of 9 previously studies, published in 2014, researchers concluded glucomannan (konjc) did not produce statistically significant weight loss benefits.
A study conducted in 2007, glucomannan was given to 42 overweight men and women, along with a diet and exercise program. The study lasted 8 weeks. These researchers used 3000 mg of glucomannan. They noted glucomannan promoted significant loses in body weight and fat compared to those who just worked out. Exercise was also seen to enhanced the effects of glucomannan.
A review article published in 2008 that included 14 studies, concluded that glucomannan was effective at reducing body weight as well as cholesterol, triglycerides and blood sugar levels.
In a review article from 2005, the researchers note that taking 2g – 4g per day of glucomannan produced significant weight loss in obese and overweight adults.
A fiber called PolyGlycopleX (PGX) is derived from glucomannan (konjac). In one small study, 5g of PGX fiber, given 2-3 times a day (10g-15g/day total) to 29 overweight people for 14 weeks produced reductions in body weight and body fat.
In a 1984 study, 1000 mg (1g) of glucomannan fiber given 3 times a day (3g total) to 20 overweight people was shown to produce significant weight loss over a 2 month period.
Lipozene Research Summary
Here is a quick summary of the research presented above.
|Study Year||Type Of Study||Study Results|
|2015||83 people/ 60days/ 3g used||Konjac works|
|2014||Review paper of 9 previous studies||Konjac does not work|
|2007||42 people /8 weeks/3g used||Konjac works|
|2008||Review paper of 14 previous studies||Konjac works|
|2005||Review paper||Konjac works|
|2010||29 people/ 8 weeks. 10-15g of PGX fiber used||Konjac PGX fiber works|
|1984||20 people/ 8 weeks, 3g used||Konjac works|
As can be seen from the table above, if konjac root extract is going to help weight, it may take 2000 mg-3000 mg before benefits are observed.
Keep in mind that none of these studies used Lipozene itself. Instead the research is on the active ingredient, which is called konjac (glucomannan)Here is konjac on Amazon
What Is METABO UP Plus?
METABO UP Plus is the other supplement mentioned on the Lipozene website and TV commercial. It's name implies that this supplement is supposed to increase metabolic rate. In fact on the product website (MetaboUp.com) they say the supplement will “increase energy and boost metabolism.”
Increased metabolic rates might – in theory – burn more calories. The more calories we burn, could in theory contribute to weight loss.
- Green tea
- Guarana seed extract (22% caffeine)
- kola nut
- vitamins B6 and B12
Metabo Up Plus contains these ingredients in 2 tablets:
|Ingredient||Amount Per Serving||Percent Daily Value|
|Vitamin B 6||600 micrograms||30% DV|
|Vitamin B12||15 micrograms||215% DV|
|Proprietary Blend Containing The Following||952 mg|
|Green tea leaf extract (50% polyphenols)|
|Guarana seed extract (22% caffeine)|
|Oolong tea leaf|
|Kola nut extract (10% caffeine)|
|Platycodon root extract (10:1)|
As can be seen, they added a couple of extra ingredients to Metabo UP Plus.
Other ingredients also present in Metabo Up Plus are: calcium carbonate, microcrystaline cellulose, stearaic acid, silicon dioxide, Croscarmellose sodium, magnesium stearate and pharmaceutical glaze.
While we are not told how much these ingredients contributes to the total amount (952 mg) of the proprietary blend, we can take a guess at which contributes the most and least. Ingredients at the top of the list contribute the most to the blend, while those at the end make up the least.
For example, since green tea is listed first, it makes up the most of the blend, while Platycodon makes up the least since it's the last ingredient listed.
What we can say about these ingredients?
The first 5 ingredients of the proprietary blend all contain caffeine. The caffeine containing ingredients in Metabo Up Plus are as follows:
- Green tea
- Caffeine (obviously)
- Oolong tea
- Kola nut
Since caffeine is a well known stimulant, all these ingredients help put the “Up” in Metabo Up Plus. To me, Metabo Up Plus looks like a caffeine supplement for the most part.
As for Oolong tea. There is at least one study showing that oolong tea can help weight loss. This study used more oolong tea than Metabo UP has.Here is Oolong tea on Amazon
The last ingredient in the blend is Platycodon. This refers to the plant called Platycodon grandiflorum. The MetaboUp.com website says it can help to “breakdown stored fat.” That might be true in mice. But what about people?
More research is needed.
What's Good / Not So Good
Here is a quick overview of what I liked and didn't care for about this supplement:
|What's Good||What's Not So Good|
|Buying 1 bottle is not too expensive||Can become expensive if used long term|
|Contains amounts of knojac used in research||Autoship program|
|Been around a long time||Lack of clinical research on Lipozene itself|
|No stimulants in Lipozene (Metabo Up Plus has stimulants)||Customer service difficult to get a hold of|
|$1.35 non refundable processing fee on returns|
How Much Caffeine?
Lipozene has no caffeine.
Metabo Up Plus has 120 mg in 2 capsules. This is roughly about what is in a cup of coffee.
Is Lipozene + Metabo Up Best?
Lipozene is often marketed with another supplement called Metabo UP or Metabo Up Plus, which was summarized above. Are both of these supplements better if taken together? I was not aware of any good proof that the Metabo Up supplement added anything to the benefits of Lipozene. In other words, I don't think people have to take both supplements.
In the research summarized above, people only took the konjac fiber, which is the active ingredient Lipozene. So, whether or not Metabo Up Plus adds anything to the effects of Lipozene is open to speculation.
How To Take Lipozene?
It's recommended to take 1 or 2 capsules with 8 oz of water at least 30 minutes before eating.
Who Makes Lipozene?
The company is called the Obesity Research Institute LLC. According to the Better Business Bureau, they are located at 4910 Longley Ln STE 101 Reno, NV 89502-7933 . Their phone number is: (800) 409-9768. The address listed corresponds to a fulfillment company called Radial. According to this FTC Press Release from 2005, the owner of Obesity Research is Henny Den Uijl.
It's ironic that given that the name “research” is in the name of the company, no published, peer reviewed clinical research for Lipozene could be uncovered at the time this review was created.
The BBB gave Obesity Research Institute a rating of “B+” when this review was created. Because ratings sometimes change, see the BBB website for updates and more information.
Lipozene.com lists the following contact numbers:
- Customer Service: 888-220-8907
- New Orders: 800-409-9768
I called both numbers and I could not reach a human. The customer service number seems to consist of a bunch of automated responses based on what keypad number you push (is it all natural? can you take it if you are pregnant? etc).
Even calling the New Orders phone number just consisted of a long winded sales pitch. I called several times and could not speak to a human.
If your interested in Lipozene, I'd say get on Amazon or at a local store.
Lipozene Return Policy
Customers have a total of 30 days to return the Lipozene weight loss pills for a refund. Return authorization numbers must be received from Customer Service and written on the shipping box. Please contact Customer Service with any questions about Lipozene's weight loss guarantee at 1-888-220-8907.
Where To Buy Lipozene
This weight loss supplement is pretty mainstream in that it should be available at most retail stores such as Walmart, CVS, GNC and the like.
How Much Does Lipozene Cost?
The website for Lipozene indicates that a bottle of Lipozene will cost $29.95. That's not too bad if compared to some other weight loss supplements like DietSpotlight Burn (click to read how much that costs). That said if buying the supplement on a regular basis, the cost will add up.
If you order, I suggest you call them rather than ordering on the website. If you do, ask if they will be adding the a non refundable fee of $1.35 to the order. If you return Lipozene within 30 days they will refund your money but not the shipping and handling you pay to send it back to them.Here is Lipozene on Amazon.
Lipozene vs. Konjac Fiber
Lipozene contains only 1 active ingredient – konjac fiber, also called glucomannan. The product does contain an amount similar to what research studies have found works, so that is good.
That said, could someone just take glucomannan and get the same results as Lipozene? I believe the answer is yes.
The konjac fiber is sold in both capsules and as a power that can be mixed into smoothies or liquids. I personally like the powder better than the capsules. Remember, the fiber swells in size when exposed to liquids.
Here is glucomannan on Amazon. glucomannan
Lipozene Side Effects
Lipozene is likely safe in most healthy people. That said, here are some potential issues to keep in mind. See your doctor if you think any of this applies to you. This list is not complete.
- Stop taking Lipozene at least 2 weeks before surgery.
- The product is not recommended for women who are pregnant/nursing.
- If you take any medications, speak to your doctor
- Metabo Up plus contains caffeine. Don't take close to bed time or if sensitive to caffeine.
- Make sure you take Lipozene with adequate water. There has been at least one report of choking with the capsules. This is likely a very rare occurrence. Glucomannan powder may be an option for those concerned about this.
- If the product caused reductions in food intake, in theory, a lowering of blood sugar may also occur. Rapid drops in blood sugar can make people dizzy as they become hypoglycemic.
Holly Robinson Peete Lipozene Commercial
Lipozene TV commercials currently feature actress Holly Robinson Peete and her husband, former football player, Rodney Peete. From some of the comments I've seen online, they have taken some heat for doing the commercial. I won't add to that because they are not the first or last celebrities to endorse weight loss supplements.
What I can say is that in the grand scheme of things, Lipozene is pretty tame compared to many other products I've seen – and it's ingredient does have some evidence.
In the past, Lipozene TV commercials have featured Stacey Travis, an accomplished actress and has appeared in many TV shows and movies that I've been a fan of over the years including Big Bang Theory, and Seinfeld. Here is her link on the internet movie database.
Does Lipozene Work?
Its possible Lipozene might help some people lose weight. That's because it contains a fiber called konjac (glucomannan) which some studies have attributed benefits to. That said, I see no evidence that the Metabo Up Plus is needed.That's good news for those who are sensitive to caffeine.