TV commercials for Lipozene say “please remember that lipozene is intended for those who seriously need to lose body-fat and weight.” That's a powerful statement because it says to me that if you only need to lose a few pounds, then lipozene may be “too strong.” That statement made me want to review Lipozene so that you would know what the TV commercials don't tell you. According to the video that is found on the Lipozene website, Lipozene is a ‘weight loss breakthrough” and is “clinically proven help reduce body fat and weight. Pretty impressive statements. Let's take a look at Lipozene and it's ingredients and Lipozene research and see what we can decipher about this weight loss supplement. Also see my review of Metamucil and weight loss for more information.
When this review was first created, Lipozene.com listed 3 studies to show that Lipozene works. Here are the studies:
- 2005 study: Glucomannan and obesity: a critical review
- 2008 study: Effect of glucomannan on plasma lipid and glucose concentrations, body weight, and blood pressure: systematic review and meta-analysis
Notice the word “Glucomannan” is in the name of each of the studies. This tells us the weight loss research is on glucomannan and not Lipozene.That's technically not a big deal because, as we'll see below, Lipozene contains glucomannan.
On the FAQ page of the product website there is mention of a company sponsored study where people lost 4.3 more pounds and 3.86 pounds of fat compared to a placebo group. But, the website does not tell us the name of the study.
Searching the National Library of Medicine (Pubmed.gov) for “Lipozene” reveals no studies. Likewise, searching ClincalTrials.gov reveals no clinical studies either.
Finally, performing an online search for “Lipozene clinical study” does not turn up any studies either.
Therefore, I'm forced to conclude at this time the Lipozene -itself – has no clinical proof that it works. That may not be a problem, because there is research on its main ingredient.
Let's look at that ingredient now.
The label of the product tells us that Lipozene has just 1 ingredient. They call it Amorphophallus Konjac. This is fancy name for a fiber called glucomannan. Other supplements might refer to its presence by simply the word “konjac” or “konjac root.”
By whatever name you call it, when it's in supplements, it refers to a fiber that expands in size – like a sponge – when it comes in contact with water. This stretches the stomach, which makes the brain think that you are full.
If we think we're full, we might not eat as much. This is the way that Lipozene and other konjac fiber supplements work.
Other weight loss supplements previously reviewed that contained this fiber include:
See those reviews for more info on those products.
Let's now review some of the research on konjac fiber and see what we can make of it.
Konjac Fiber Research
There is research on konjac fiber and weight loss. Remember the other name for this fiber is glucomannan.
In a 2015 study, 83 overweight men and women were given either konjac supplements or a placebo for 60 days. The amount of konjac used was 3000 mg (3g) a day. These researchers noted that the konjac supplements caused significantly more weight and fat loss than those who took the placebo.
A study conducted in 2007, glucomannan was given to 42 overweight men and women, along with a diet and exercise program. These researchers used 3000 mg of glucomannan. They noted glucomannan promoted significant loses in body weight and fat compared to those who just worked out. Exercise was also seen to enhanced the effects of glucomannan.
In a 1984 study, 1000 mg (1g) of glucomannan fiber given 3 times a day (3000 mg total) to 20 overweight people was shown to produce significant weight loss over a 2 month period.
The fiber called PolyGlycopleX (PGX) is derived from glucomannan. In this 2010 study, 5g of PGX fiber, given 2-3 times a day to 29 overweight people for 14 weeks produced reductions in body weight and body fat.
To be fair, not all studies note that konjac helps weight loss. For example, in this 2014 review of previous investigations, it was concluded that there was not enough evidence to state that there was indeed a positive effect. This dependency may be due problems with how the various studies were conducted or the amounts of konjac used.
That said, if konjac fiber is going to help it appears that close to 3000 mg would have to be used. This is what is found in two capsules of Lipozene.
What Is METABO UP Plus?
METABO UP Plus is the other supplement mentioned on the Lipozene website and TV commercial. It's name implies that this supplement is supposed to increase metabolic rate. Increased metabolic rates might – in theory – burn more calories. The more calories we burn, could in theory contribute to weight loss.
METABO Up -the original product marketed – appears to have been replaced by Metabo Up Plus. The METABO UP supplement contained these ingredients:
- green tea
- kola nut
- vitamins B6 and B12
The Metabo Up Plus supplement contains these ingredients in 2 tablets:
|Ingredient||Amount Per Serving||Percent Daily Value|
|Vitamin B 6||600 micrograms||30% DV|
|Vitamin B12||15 micrograms||215% DV|
|Proprietary Blend Containing The Following||952 mg|
|Green tea leaf extract|
|Guarana seed extract|
|Oolong tea leaf|
|Kola nut extract|
|Platycodon root extract|
Other ingredients also present in Metabo Up Plus are: calcium carbonate, microcrystaline cellulose, stearaic acid, silicon dioxide, Croscarmellose sodium, magnesium stearate and pharmaceutical glaze.
While we are not told how much these ingredients contributes to the total amount (952 mg) of the proprietary blend, we can take a guess at which contributes the most and least. Ingredients at the top of the list contribute the most to the blend, while those at the end make up the least.
For example, since green tea is listed first, it makes up the most of the blend, while Platycodon makes up the least since it's the last ingredient listed.
What we can say about these ingredients?
The first 5 ingredients of the proprietary blend contain caffeine. The caffeine containing ingredients in Metabo Up Plus are as follows:
- Green tea
- Caffeine (obviously)
- Oolong tea
- Kola nut
Since caffeine is a well known stimulant, all these ingredients contribute much to the “Up” in Metabo Up Plus. To me, Metabo Up Plus looks like a caffeine supplement for the most part.
Besides the caffeine, one ingredient that is interesting is Oolong tea. There is some research that Oolong tea can help weight loss.Here is Oolong tea on Amazon
How Much Caffeine?
Lipozene has no caffeine but Metabo Up Plus has 120 mg in 2 capsules. This is roughly about what is in a cup of coffee.
Who Makes Lipozene?
The company is called the Obesity Research Institute LLC. According to the Better Business Bureau, they are located at 4910 Longley Ln STE 101 Reno, NV 89502-7933 . Their phone number is: (800) 409-9768. The address listed corresponds to a fulfillment company called Radial. According to this FTC Press Release from 2005, the owner of Obesity Research is Henny Den Uijl.
It's ironic that given that the name “research” is in the name of the company, no published, peer reviewed clinical research for Lipozene could be uncovered at the time this review was created.
The BBB gave Obesity Research Institute a rating of “B+” when this review was created. Because ratings sometimes change, see the BBB website for updates and more information.
This is the number of Lipozene customer service 1-800-409-9768.
Lipozene Return Policy
I recommend calling customer Lipozene Customer service before returning any products. That way you will know the best way to do this.
Also, the 30 day guarantee is only good if you purchase Lipozene from the Lipozene website or from TV commercials. In other words, if you buy it from a store or online, the guarantee is not honored. That said, most stores and online retailers, like Amazon, have return policies.
How Much Does Lipozene Cost?
The website for Lipozene indicates that a bottle of Lipozene will cost $29.95. If you order, I suggest you call them rather than ordering on the website. If you do, ask if they will add a “fuel surcharge' of $1.35 to each order they receive. If you return Lipozene within 30 days they will refund your money but not the shipping and handling you pay to send it back to them.Here is Lipozene on Amazon.
Lipozene vs. Konjac Fiber
Lipozene contains only 1 active ingredient – konjac fiber, also called glucomannan. The product does contain an amount similar to what research studies have found works, so that is good. For those who are wondering, one could just take glucomannan and get the same results as Lipozene.
The fiber is sold in both capsules and as a power that can be mixed into smoothies or liquids. I personally like the fiber better than the capsules. Remember, the fiber swells in size when exposed to liquids.
There have been isolated reports of a choking hazard from the capsules. While I think this possibility is remote, that is why I prefer the fiber over the capsules. For those who use the capsules, just make sure to drink a full glass of water to minimize any risk of this occuring.
Here is glucomannan on Amazon. glucomannan
Is Metabo Up Plus Needed?
Lipozene is often marketed with another supplement called Metabo UP or Metabo Up Plus, which was summarized above. Those who might be sensitive to caffeine and may wonder if they have to take this supplement. At the time this review was created, I was not aware of any good proof that the Metabo Up supplement added anything to the benefits of Lipozene. In other words, I don't think people have to take both supplements. In the research summarized above, people only took the konjac fiber supplement, which is the active ingredient Lipozene.
Lipozene Side Effects
I was not aware of any negative side effects from Lipozene when this review was created. For most healthy people, I think the product is quite safe. That said, here are some potential issues to keep in mind. See your doctor if you think any of this applies to you. This list is not complete.
Stop taking Lipozene at least 2 weeks before surgery. The product is not recommended for women who are pregnant/nursing.
Glucomannan is a fiber that expands greatly when it comes in contact with water. As I mentioned in my review of Glucosulin, in theory, this could be dangerous if the pill becomes lodged in the throat. This is one reason why I like glucomannan powder more than capsules.
If the product caused reductions in food intake, in theory, a lowering of blood sugar may also occur. Rapid drops in blood sugar can make people dizzy as they become hypoglycemic.
Metabo Up contains caffeine. Don't take close to bed time.
Who's The Women In The Lipozene Commercial?
Past TV commercials for Lipozene featured Stacey Travis. She is an accomplished actress and has appeared in many TV shows and movies that I've been a fan of over the years including Big Bang Theory, and Seinfeld. Here is her link on the internet movie database.
Does Lipozene Work?
Lipozene contains a fiber called konjac (glucomannan) which some studies have noted may help people lose weight. Two capsules of Lipozene also contain an amount of konjac which is in line with what studies have used too. I see no evidence that the Metabo Up Plus is needed. It's worth mentioning that the active ingredient in Lipozene – konjac/glucomman fiber – can be purchased alone. This may be important to those who feel Lipozene is too expensive. Here is Konjac on Amazon..Here is Lipozene on Amazon