Ceraplex is said to be a brain-specific antioxidant compound can help detoxify your brain and help protect it from environmental toxins and the aging process. Doing so might help the brain work better as we get older. Sounds good, but does Ceraplex work? That's the question I'll try to address in this Ceraplex review. Also see my reviews of Cebria, Nerium EHT and Prevagen for more information on those supplements.
Who Makes Ceraplex?
Ceraplex is a product of Brain Research Labs. (brainresearchlabs.com). This is the same company that makes the brain supplement called Procera AVH.
The address listed for Brain Research Labs is 12002 N. Riverwood Dr. Spokane, WA 99218. Here is what the address looks like according to google maps.
As you can see, this address corresponds to a house. Not what I'd expect from a company with the name “Brain Research Labs.”
As an aside, I'd mention that this address is completely different from the address than was listed for Brain Research Labs when I investigated Proccea AVH. That address was in Tennessee.
Things get more complicated when you look up Brain Research Labs on the Better Business Bureau website because here, you will see another completely different address. On the BBB website, they list their address as 15820 Euclid Ave, Chino, CA 91708.
if you Google the Chino California address you discover that it's the address of a completely different company called “Motivational Fulfillment and Logistics Services” (mfals.com).
The website of this company was ” temporarily unavailable” when I wrote this review, but the word “fulfillment“ in the title makes me think this is the company that actually ships Ceraplex to customers.
For more info on Brain Research Labs see my review of Procera AVH.
According to the Brain Research Labs website, Ceraplex is composed of these 6 ingredients:
- Alpha lipoic acid
I can't tell from the product website how much of each of these ingredients is in Ceraplex.
All of these ingredients have antioxidant and /or anti-inflammatory properties. It seems to me that these ingredients were chosen in the hopes that they would reduce free radical damage, which in turn might reduce cellular inflammation, thereby reducing damage to the brain. That’s at least my theory. Take it for what it's worth.
I searched the website of Brain Research Labs and could not find any published peer reviewed research on Ceraplex itself. I also searched the National Library of Medicine for “Ceraplex” and likewise, no studies could be found.
Thus, I'm forced to conclude Ceraplex —itself —has no good proof to substantiate any of the claims for its benefits. That doesn’t necessarily mean it doesn’t work, but rather that nobody seems to have tried to prove it to my satisfaction.
There is however research on the ingredients of Ceraplex. Let's now look at some of the relevant research on each ingredient in Ceraplex and see what we can discover.
Alpha Lipoic Acid
When used long term, alpha lipoic acid seems to help some people who have Alzheimer's disease according to a very small study (43 people) who were given 600 mg / day for 2 years. That said, an earlier review of alpha lipoic acid and dementia research found no good proof that it worked in light of the lack of quality research.
Brain Research Labs says Ceraplex has “R-Alpha Lipoic Acid (R-ALA).” The letter “R” is science talk that’s sometimes used to refer to the natural form of a nutrient.
N-Acetyl-Cyesteine appears to reduce levels of homocysteine, a compound that seems to play a role in heart disease. But, research so far, does not show that N-Acetyl-Cyesteine helps Alzheimer's disease. Most of the research on this nutrient and dementia is based on preliminary research. Thus better studies are needed to say if it helps dementia or not.
This herb is also called tumeric. Tumeric has anti-inflammatory qualities. For this reason, this curcumin is sometimes found in arthritis supplements. The idea here might be that reducing brain inflammation might reduce the risk of dementia. That said, one preliminary study noted that 6 months of curcumin use did not help Alzheimer's disease.
Tip. Research shows that regular exercise reduces inflammation in the brain.
Resveratrol (the scientific name is trans-3,4′,5-trihydroxystilbene) is the classic anti-aging supplement. Like a lot of the other ingredients in Ceraplex, resveratrol is an antioxidant. Of interest to this discussion, one study —in rats —noted that resveratrol reduces blood vessel aging by reducing free radical damage. That’s good.
Other research suggests that resveratrol helps clear the plaques —that clog up nerve pathways —that are characteristic of Alzheimer's disease. That's good too. How resveratrol seems to work is under investigation, however some speculate that it may work by activating genes in a similar way as reducing calories.
Does cutting back on calories reduce Alzheimer's in people? It's an interesting question that deserves more research. Resveratrol continues to be a hot topic in research, but as far as I can see, there is no consensus on how much resveratrol helps Alzheimer's disease or other forms of dementia. for more info, see my resveratrol review.
Like resveratrol, quercetin is also an antioxidant and found in red wine as well as several foods. Unlike resveratrol, there appears to be less dementia-related research on quercetin. One study speculated that quercetin might protect brain cells. Other research finds quercetin can lower blood pressure in humans.
Reducing blood pressure would lead to less stress on blood vessels, which might reduce blood vessel damage in the brain and elsewhere. This might play a role in reducing or delaying dementia symptoms.
Obviously, the effects of quercetin are likely to be much more complicated than this. To achieve this blood pressuring effect, about 700 mg of quercetin per day has been used. How much quercetin is in Ceraplex? I don't know.
This is basically a form of vitamin B12. I believe that vitamin B12 is in Ceraplex because this vitamin can help reduce homocysteine levels.
The vitamins B6 and folic acid also reduce homocysteine too.
Homocysteine seems to take part in heart disease and damage blood vessels. Damaging blood vessels in the brain might play a role in dementia.
While we usually stockpile a few years worth of vitamin B12, research finds some older adults eventually run out of it due to an inability to absorb this vitamin. All that said, one study from 2011 did not show that methylcobalamin reduced dementia symptoms in older adults with dementia.
Likewise an earlier study from 2007 also noted no significant effect of vitamins B12, B6 or folic acid in people with mild to moderate Alzheimer's disease.
Side note. Does Vitamin B12 help weight loss? Read my review.
Ceraplex Side Effects
The product website says that Ceraplex has no known side effects but cautions people who take blood thinner medications to see their doctor first. To that list, I’d like to add some of these other possibilities. Stop taking all supplements not prescribed by your doctor at least two weeks before having surgery.
Alpha lipoic acid might lower blood sugar. While this is generally good, it might be a problem for diabetics. This is why this nutrient is in sometimes marketed to diabetic and overweight individuals. One such product I've already reviewed is Plexus Slim.
Alpha Lipoic Acid might also reduce thyroid hormone.
N-acetyl cysteine might reduce blood pressure and interact with blood pressure lowering medications.
Resveratrol has a weak estrogen-like effect. Women with a history of breast cancer or other cancers should consider this before using Ceraplex. Read my resveratrol and cancer review for more information.
Quercetin might interact with tissue rejection drugs.
I don't know if Ceraplex has any of these effects. Odds are, it doesn’t. My hope is that these findings reinforce the idea to get checked out by your doctor first especially if you have any health problems.
Ceraplex AndProcera AVH: Better Together?
The Brain Research Labs website says Ceraplex is “perfect compliment” to Procera AVH however they give no proof that this combination works better. It might, but again, where is the scientific proof?
How Much Does Ceraplex Cost?
When I wrote this review, the Brain Research Labs website had a price of $59.95 plus shipping & handling if you wanted to order only a one month supply of Ceraplex.
If you wanted to become a “power saver” the cost is $39.95 per month plus shipping & handling. Note, the power saver option means they will automatically ship you a month of Ceraplex every month until you tell them to stop. To cancel the auto shipments you should call their customer service at 1-800-213-4101.
For those who want to compare prices and avoid the autoship program, here is Ceraplex on Amazon.
How To Contact Brain Research Labs
If you need to return Ceraplex or contact Brain Research Labs, their Customer Service Department at 1-800-213-4101 (M-F 9A-7P EST or Saturday 9A-7P EST).
This is the address they use for Ceraplex : BRAIN RESEARCH LABS. 15820 Euclid Avenue. Chino, CA 91708.
Does Ceraplex Work?
Ultimately, I don't know if Ceraplex works or not because I can't locate any studies on Ceraplex itself. There is research on the ingredients in Ceraplex. Based on the research I saw, I'd say the strongest evidence is for resveratrol and after that, alpha lipoic acid.
That said, I can't speak to how much resveratrol or alpha lipoic acid would help memory, brain health or reduce brain aging. I don't think anyone can at this point.
For those who want to keep their brain working well as they get older, here are 3 things you can right now that don't cost $39.95 per month or have an auto ship program. These things are also based on science. In no special order here they are:
You may notice that these 3 things also help your heart stay healthy too. That’s no coincidence given that growing evidence suggests a link between brain health and heart health. Can Ceraplex fit into this regimen? Maybe. But I would not just use Ceraplex at the expense of having an overall healthy lifestyle.
Ceraplex is on Amazon for those who are interested and want to see what others are saying.
What do you think?