I never know where I’m going to get ideas for reviews. Take Andro400 for example. I first heard the Andro400 radio commercial as I sat in a doctor’s office waiting for a checkup. The product was said to help not only with belly fat and weight loss but also alleviate issues of low testosterone too. Does it work? I must admit Andro400 did not contain what I thought it did. If you were also curious of this product, keep reading and discover what I found.
I searched the National Library of Medicine for “Andro400” but did not see any clinical studies showing up on the product. I then googled “Andro400 research” but this likewise didn’t reveal any research on the product either. I also tried to find research on the product at ClinicalTrials.gov, but without success.
As such, I conclude that Andro400– itself – has no research. That said, there may be research on the ingredients in the product. So let’s look at that now.
When I first heard the name of this supplement, my guess was that it that contained androsteinedione, known in bodybuilding circles as “Andro.” I was wrong. Andro 400 does not contain andro. Rather, according to its website – Andro400.com – 1 capsule contains these 3 ingredients:
- Eurycoma longifolia 250 mg
- L Arginine 250 mg
- L Citrulline 250 mg
The recommended amount to take is 2 capsules per day. As such, taking 2 capsules provides:
- 500 mg of Eurycoma longifolia
- 500 mg of L arginine
- 500 mg of L citrulline
Or, 1500 milligrams of everything per day.
Since none of the ingredients equals 400 mg, I’m not sure where the “400” in the name comes from.
As their customer service department informed me, there are two different forms for this product. There are:
- Andro400 Max
The difference is that the regular formulation only contains Eurycoma longifolia. Andro400 Max – which is what I’m reviewing here –contains the 3 ingredients listed above.
Since Andro400 is primarily supplement marketed to raise testosterone levels, let’s now review the research on each of these ingredients as they pertain to testosterone.
Take notice of the amounts used in the studies.
Other names for this herb are Malaysian ginseng, Lonjack and Tongkat Ali. This herb is very popular in testosterone supplements and those geared for “Low T” as is evidenced by reviews on these other supplements I’ve looked at previously:
- Regimen (click to read review)
- Syntheroid (click to read review)
- Triverex (click to read review)
To get a better idea if the Andro400 works or not, I searched the national library of medicine for :
- Eurycoma longifolia testosterone
- Longjack testosterone
- Tongkat Ali testosterone
I found the following human research studies:
A 2014 study titled Supplementation of Eurycoma longifolia Jack Extract for 6 Weeks Does Not Affect Urinary Testosterone: Epitestosterone Ratio, Liver and Renal Functions in Male Recreational Athletes. The title speaks for itself, but in a nutshell, for 6 weeks, 13 healthy non-athletes (recreational athletes) (average age about 29 years) were given either a placebo or 400 mg of Eurycoma longifolia (For 6 weeks they got the supplement and for 6 weeks they took a placebo). The study used a specific supplement called “Physta” made by Biotropics Malaysia Berhad.
Results: Eurycoma longifolia had no effect on testosterone levels as measured in the urine.
A 2014 study titled Tongkat Ali as a potential herbal supplement for physically active male and female seniors–a pilot study. In this investigation, 13 males and 12 females (57-72 years of age) were recruited. All were physically active individuals.
Results: After 5 weeks of use, 400 mg of tongkat ali (eurycoma longifolia) increased testosterone levels in both men and women.
This study differs from the one above it. this might mean that eurycoma longifolia works differently in older vs. younger people.
While this is an interesting study, one possible problem is that there was no placebo group to compare the results. In theory, this may have influenced some of the outcomes in the study.
A 2013 study titled Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. Here, 64 men and women were randomly given either a placebo or 200 mg of a eurycoma longifolia supplement (the supplement used was Physta, made by Biotropics Malaysia Berhad). The study lasted 4 weeks.
Results: These researchers noted that the Physta supplement increased testosterone levels (by 37%) as well as improving various aspects of mood. It’s worth noting that this study showed no changes in body fat. This appears to contradict claims that Andro400 helps weight loss.
One possible drawback this study is that it did not mention the ages of the participants. Knowing this would make it easier to compare these results to those taking part in other studies.
Based on this research, if eurycoma is going to work, its effects might be greatest in older adults and when used amounts greater than 400 mg per day. Do see the other reviews linked to above, for additional insights.
Arginine and L Citrulline
Both of these are non-essential amino acids (we make them) and are common in anabolic hormone booster supplements. Let’s address each separately.
Also called “L arginine.” Arginine is reputed to increase growth hormone levels. I covered arginine in my review of SeroVital so see that for additional information.
Trivia: The “L” in the name is chemistry talk and means the molecule is “left handed.” All the muscle building amino acids in our body are left handed. Pretty neat.
Arginine also helps us make nitric oxide, a gas that expands blood vessels. Because of this fact, arginine is popular in male performance supplements (erection supplements) too. For more on nitric oxide, see my review of SuperBeets.
That said, either way you look at it, 2 capsules of Andro400 is only providing 500 mg of arginine, which isn’t a lot. To contrast, studies showing improvement in erection problems have used about 5 grams a day. Studies of arginine improving growth hormone levels have also used a lot of it, between 5-9 grams per day.
This amino acid helps us make arginine. As such, I think one reason supplements contain citrulline is that, by helping us make arginine, it might help us also raise growth hormone levels.
Because it can also improve nitric oxide levels (by helping us make more arginine), citrulline is also found in erection supplements too. Like, arginine, it might help erections, although most of the studies I saw involved lab rats.
In this 2011 study, titled, Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction, 1.5 grams of citrulline was shown to improve erections in men compared to a placebo.
As for its effects on growth hormone, this may be open to speculation. In this 2011 study titled, Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study, 15 grams did not appear to raise growth hormone levels in a small group of men.
The 15 grams used in this study is a lot more than the 500 mg of citrulline contained in 2 capsules of Andro 400.
Andro400 and Belly Fat
I am not aware of any good proof that Andro400 or its ingredients targets belly fat, causing weight loss from this region of the body.
Andro400 and Women
I’m not aware of any good proof that Andro400 or its ingredients improves sexual function or alters testosterone levels in women. Likewise, I am not aware of any good proof that the ingredients promote weight loss either.
How Much Is Andro 400?
When I wrote this review, the product website had these prices:
- Andro 400: $29.95 per month
- Andro 400 Max $34.95 per month
Ordering from the Andro400.com website does enter people into an autoship program where they will ship a new bottle each month until you cancel. To contact Andro400 customer support, call 888-400-0435.
To compare prices, here are the ingredients on Amazon:Here is Eurycoma longifolia
Here is Arginine on Amazon
Here is Citrulline on Amazon
Who Makes Andro400
According to the product website, the company is called Natural Health Solutions. Their address is: 5407 N. Haverhill Rd, suite 336 West Palm Beach, FL 33407. When I googled this address, I found that it corresponds to another company, called Z Natural Foods (znaturalfoods.com).
When I called Andro400 customer support, they confirmed that National Health Solutions and Z Natural Foods are the same company.
The Better Business Bureau gives Z Natural Foods a rating of “A+” when I wrote this review. See the BBB file for updates and additional information.
Andro 400 Guarantee
The product website states that Andro 400 comes with a 90 day money back guarantee. The bottles can partially empty, or completely empty. That’s good. People have to return the bottles to the company to be eligible for the refund.
It is important to remember that the 90 day guarantee stats the day you order the product – not when it arrives. Contact customer support for more on this. You can reach them by calling 800-400-0435 or emailing them at Support@andro400.com.
How to Contact Andro 400
The Andro400.com website lists this phone number for customer support: 888-400-0435. You can also email them at Support@andro400.com too. I recommend calling. I found their customer service people very responsive to calls and questions.
Andro400 Side Effects
I’m not aware of any side effects from taking Andro400. When I searched online I didn’t see much about side effects either. That said, below is a list of theoretical side effects that some people might notice. This list is not complete. Speak with your doctor and/or pharmacist if you think any of this applies to you:
People who take blood pressure lowering medications should speak to their doctor/pharmacy. Arginine may reduce blood pressure.
Arginine might have a blood thinner effect. This might interfere with blood thinner medications.
People who have had a heart attack should speak to their doctor before using arginine supplements.
Arginine might cause flair ups of the herpes virus
Does It Work?
I didn’t try Andro400 so I can’t know for sure, but based on the research I saw, if it’s going to work –by that I mean if it’s going to raise testosterone – I believe Eurycoma longifolia is likely the active ingredient. That is not an endorsement of this herb because, as I tried to show above, not all the research shows it works. If it works, I feel its effects might be more pronounced in men with lower testosterone levels. I don’t feel arginine or citrulline add anything to the effects because I don’t feel the product has enough of these amino acids to raise hormone levels.
All that said, if you are going to try Andro400 (or eurycoma longifolia) I suggest you get your testosterone levels checked now – before you start the product – and measure them again a month later. At the end of the day, this is the only way to really know if it works or not.
Here is eurycoma longifolia on Amazon to compare prices.