Ageless Male is a testosterone enhancer for men over 40 that you may have seen advertised on Fox and Friends and elsewhere. Its bottles claim it to be a “worldwide best seller.” Since I first reviewed Ageless Male, its ingredients have changed quite a bit, so this updated review will first list the new ingredients and their research and after that I'll show you the ingredients in the original formula. Does Ageless Male really work? Does It raise testosterone levels or improve libido? Does it have any side effects? Let's look at the ingredients in this testosterone booster and see what we can discover.
What Is Ageless Male?
Ageless Male is a supplement primarily marketed to men over 40 who have low testosterone levels – or who think they do. According to the products website, Ageless Male is alleged to have these benefits:
- Boost Healthy Testosterone Levels.
- Increase libido, drive and performance.
- Helps Promote Energy Metabolism.
- Promotes Muscle as Part of Strength Training.
All of these claims contain an asterisk that refers readers to the statement that “these statements have not been evaluated by the Food and
Ageless Male Ingredients
A bottle of Ageless Male has 60 tablets. Each 1 tablet of Ageless Male has the following ingredients:
|Ingredient||Amount Per Serving||Percent Daily Value|
|Vitamin B 6 (pyridoxine HCL)||4.9 mg||245% DV|
|Magnesium (magnesium oxide)||16 mg||4% DV|
|Zinc (zinc acid chelate) 15 mg||15 mg||100% DV|
|Fenugreek seed extract (as Testofen. Standardized fenugreek seed extract)||300 mg||N/A|
N/A = no daily value established
Other Ingredients in Ageless Male that are listed are:
- calcium carbonate
- microcrystalline cellulose
- stearic acid
- croscamellose sodium
- magnesium stearate
- coating (hypromellose & polyethylene glycol)
I don't believe these ingredients play any role in the effects of Ageless Male.
Ageless Male Vitamins And Minerals
While I normaly don't review the vitamins and minerals in supplements (becuase I don't think they do anything), there is some evidence on the nutrients in Ageless Male so here is a quick review of them to help you better understand why they are present.
Ageless Male contains the mineral zinc. Zinc is also found in other testosterone enhancer supplements too. The reason for this is probably because of a study from 1996 that looked noted zinc supplementation raised testosterone in both younger and older men who were lacking this mineral.
In this study, the older men were naturally lacking zinc but it had to be induced in younger men. In other words, the younger men were not deficient in zinc.
While older adults might be deficient in zinc, becuase they might not eat so well, Im not convienced younger men need more of this mineral.
Foods naturally rich in zinc include seafood, pumkin seeds, chicken and beef nuts and beans to name a few.
In rats, lack of vitamin B6 might reduce testosterone production. But what about people? Does B6 raise testosterone in humans? If that evidence exists, it could not be located for this review.
Foods high in vitamin B6 include meats, chicken, fish, chickpeas and potatoes.
One study involving 30 men (18-22), noted that magesium (10 mg per kilogram of body weight), raised both free testosterone and total testosterone. Both exercise alone (carried out to exhaustion) and exercise + magnesium increased testosterone levels. The higest levels were seen in those who exercised to exhaustgion and took magneiuim supplements. No signifant changes were seen in those who took magnesium but did not exercise.
Two tablets of Ageless Male (recommended amount to take) contain 30 mg of magneium. This study used much more than this. The men in this study used 10 mg per kilogram of body weight. So, a 180 pound man (82 kg) would have recieved 818 mg of magnesium per day.
Regimen is another popular low T supplement. See that for more information.
What Is Testofen?
Testofen is the name given to a trademarked form of the herb fenugreek. The scientific names for fenugreek are Trigonella foenugraecum and Trigonella foenum-graecum. Keep these terms in mind during as the Testofen research is reviewed below. Two other names for fenugreek that's sometimes used is Greek hay and Greek hay seed.
Testofen is a registered trademark of the company Gencor Pacific (GencorPacific.com). In other words, Gencor Pacific created the name “Testofen” as a way to subtly drive home the message that this extract of fenugreek raises testosterone.
But does it?
Let's look at some the research on fenugreek and testosterone and try to find out
Searching the National Library of Medcieine (pubmed.gov) for:
- Testofen testosterone
- Fenugreek testosterone
- Trigonella foenugraecum testosterone
- Trigonella foenum-graecum testosterone
I located the following studies that will be reviewed below.
In a study published in 2011 in the Journal Phytotherapy Research, fenugreek was randomly given to 60 healthy males between the ages of 25 and 52 for 6 weeks. Men either received fenugreek (600 mg of Testofen) or a placebo and they rated how they felt on a sexual functioning questionnaire (called the DISF-SR) over the course of the 6 week study.
Men who received the fenugreek extract reported greater feelings of sexual arousal, orgasm, libido, well being, energy and muscular strength. There was no change in mood reported.
It is odd that the men in the study reported no change in mood, yet they reported better “well being.” To me, that does not compute. How does well being improve, but not your mood?
Keep in mind that this study did not directly measure strength or energy levels. Rather, the men just reported that they felt stronger and had more energy. This is a drawback of the study.
While these points are interesting, the study also says that testosterone levels did not change.
In the study they say “Serum prolactin and testosterone levels remained within the reference range.” That's fancy talk for ” Testofen did not raise testosterone levels.” Even scientists tap dance around the facts sometimes—and this is an example of it.
Fenugreek is an example of a natural 5 alpha reductase inhibitor. The enzyme 5 alpha reductase is turns testosterone into DHT (di-hydro-testosterone). Thus, anything that could inhibit the 5 alpha reductase enzyme might prevent DHT formation and — elevatetestosterone levels.
The next study looked at how well fenugreek can block 5 alpha reductase enzyme.
This study was published in the International Journal of Sports Nutrition and Exercise Metabolism in 2010. It involved 30 college age males who were randomly given 500 mg of fenugreek extract —or placebo—for 8 weeks.
The extract of fenugreek used in this study was called grecunin. The word grecunin looks a lot like graecum, which is part of the scientific name for fenugreek (Trigonella foenum-graecum).
Food for thought: I don't know if fenugreek supplements tell how much grecunin they contain.
In this study the men lifted weights for 4 days per week for 8 weeks. They took the fenugreek extract in the morning and just prior to working out. At end of the study, men who received fenugreek extract, saw these benefits:
- 6.57% increase in testosterone —a significant change
- 12.26 increase in the bio-availability of testosterone —a significant change
- 1.77% decrease in body fat —a significant change
- 26.62% increase in estrogen (estradiol) — a non -significant change
- 6.10 % increase in DHT —a non-significant change
- No significant change in muscle strength in the upper or lower body
- No significant change in protein synthesis or muscle hypertrophy
The researchers also noted that fenugreek did not completely block the action of 5 alpha reductase. It partially blocked the action of the
enzyme—which is interesting— but did not block it completely. This study was funded by Indus Biotech, a pharmaceutical company based in India. Indus Biotech also provided the fenucreek extract. The study lists no conflicts of interest among the researchers (that's good).
This study is interesting. If you decide to try fenucreek remember that the people used in this investigation were college age males. I don't know if the same results would occur in men who are, say, in their 50s.
Researchers in 2016 published a study on Testofen that lasted 12 weeks and involved giving either a placebo or 600 mg of the fenugreek extract to 111 healthy men (43-70 years of age). Testosterone was measured before and after the study and men completed a questionnaire (the Aging Male Symptom Questionnaire) designed to gauge their sexual function and other feelings of low hormone levels.
Compared to those taking a placebo, men taking Testofen reported more morning erections and improvements in their andropause questionaries. Researchers also reported a “small but significant difference” in testosterone in those taking Testofen compared to those taking a placebo.
In 2017, researchers in India, noted that a fenugreek extract supplement called Furosap raised testosterone levels between 45% and 90% and improved sperm motility . This study involved 50 men (35-65 years of age) who were given 500 mg of the Furosap supplement for 12 weeks. Furosap is a product of a company called Cepham (Cepham.com) which is located in New Jersey. I found it odd that they went to India to do their study. A problem with the study was that there was no placebo group.
This supplement contains Furosap for those interested.
Testofen Research Summary
Research can be complicated so here is a quick rundown of the research on Testofen/fenugreek and testosterone
|Physiological aspects of male libido enhanced by standardized Trigonella foenum-graecum extract and mineral formulation (2011)||600 mg Testofen / placebo||no change in testosterone. men reported feeling better though.|
|Effects of a purported aromatase and 5α-reductase inhibitor on hormone profiles in college-age men. (2010)||500 mg fenugreek extract / placebo||6.5% increase in testosterone, 12% more bio-available testosterone, 1.7% decrease in body fat. No change in muscle strength/muscle growth. Partial blocking of the 5 alpha reductase enzyme|
|Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study. (2016)||600mg Testofen/placebo||men reported better morning errections and felt better. "small but significant" change in testosterone levels|
|Efficacy of FurosapTM, a novel Trigonella foenum-graecum seed extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Volunteers. (2017)||500 mg fenugreek supplement called "Furosap"||45-90% improved testosterone / better sperm motility. This study had no placebo group.|
My Fenugreek Experiment
While writing this review I became interestred in the reseach I was seeing. So, just as an experiment, I purchased the Vitamin Shoppe brand of fenugreek (not the same thing as Ageless Male) and took 610 mg per day for 6 weeks to see what happens. While I did notice a little change in erections (usually in the evening), I thought it was minimal and I would not call the effect “significant”. I did not measuire my testosterone levels during this “experiment.”
Might the ingredients in Ageless Male work together better than just fenugreek alone? It's possible. I did not test drive Ageless Male so I can't say for sure.
Ageless Male Ingredients (Old Formula)
This review of Ageless Male would not be complete if I didnt mention that the version of the product we see today is not the same as it origionaly was when I first reviewed it. Back then, the origional Ageless Male formula contained only 2 ingredients, which together form a proprietary blend that was called “Re-Settin.”
The ingredients in the Re-Settin blend were:
- Saw Palmetto berry extract
- Astaxanthin (a type of carotenoid)
Re-Settin is a catchy word. I guess these ingredients are supposed to “reset” a man’s testosterone levels? Regardless, Re-Settin is a marketing word that is holds no scientific meaning.
Originally, 2 capsules of Ageless Male had 10 calories and 800 mg of the Re-Settin blend of ingredients.
The version of the product today has no similarlity to what was in the product previously. I have no way of knowing if how new version of Ageless Male compares to the orgigional formula.
Regardless, here is a review of the research I could turn up on the ingredients in the orgional formula.
Ageless Male Research (Old/Origional Formula)
The original formula of Ageless Male -the product itself – appeared to have no published, clinical proof that it raises testosterone in humans. Searching online, clinicaltrials.gov and Pubmed.gov revealed no clinical studies on the product.
There does appear to be one study on saw palmetto and astaxanthin and testosterone levels. The study was published in 2008 in the Journal of the International Society of Sports Nutrition.
The study did not use Ageless Male. Rather researchers were testing another supplement called Mytosterone (also called AlphaStat) made by a company called Triarco (triarco.com) which is located in Wayne NJ. Triarco funded this study but the investigation notes that none of the authors had any financial connection to the outcomes of the research (that's good).
In this 2 week long investigation, 42 healthy men between the ages of 37 and 70 were divided 2 groups.
- Group 1 (21 men) were given 800 mg of the Mytosterone supplement
- Group 2 (21 men) were given 2000 milligrams of the Mytosterone supplement
At the end of the study, researchers noted that men who got both 800 mg and 2000 mg showed:
- Significant elevations in testosterone
- Significant reductions in DHT
However, significant reductions in estrogen were only seen in men who received the 2000 mg dose.
No significant side effects were noted but again this study lasted only 2 weeks.
If this was a the study that Ageless Male ingredients was based on, keep in mind that it did not look at sex drive, bone growth, strength or muscle development or most other things Ageless Male is supposed to improve. Myosterone may be found in other supplements also but do check the levels in supplements to make sure you are getting at least 800 mg.
This study did raise some red flags with me. For one thing, the researchers say that the men were divided into two groups. They do not say that the men were randomly divided into the groups. I'm mentioning this because if you look at both groups, they have “significantly different” testosterone levels at the start of the study.
- Group 1 (whose average age was 55) testosterone level =21.64 nmol/L
- Group 2 (whose average age was 61) testosterone level =26.26 nmol/L
I’d expect that if the men were randomly assigned to each group, that there would not be a significant difference in testosterone levels between groups.
Also, there was no control group either. Given the differences in testosterone between groups at the start of the study, a control group (who got nothing) would make me feel a little better about how good this study was.
Because of my reservations, I’d like to see a few studies replicate these findings before I Mytosterone it 2 thumbs up. I’d also like to see what happens in a group of men who lift weights while taking Mytosterone.
Who Makes Ageless Male?
Ageless Male is marketed by a company called New Vitality (NewVitality.com) which incidentally also goes by the name NAC Vitamin Company (also called NAC Marketing company) according to the Better Business Bureau. The BBB gave NAC Vitamin Company a rating of “B+” when this review was written. Check the BBB file for updates and more information
According to their Whois.com file, New Vitality/NAC Vitamin company is located at 95 Executive Drive, suite 14 11717. If you google the address (minus suite 14) you can see what it looks like.
Another address for New Vitality is 260 Smith St., Farmingdale, NY 11735. Googling this address clearly shows a building with a sign saying “New Vitality, NAC Marketing.”
It's worth mentiong that Ageless Male is one of MANY products New Vitality offers.
Super Beta Prosate is another supplement marketed by New Vitality. See that review for more information.
How To Contact Ageless Male?
New Vitality, the company that markets Ageless Male can be reached at 800-675-5956. Another phone number is 631-777-7767.
How Much Does Ageless Male Cost?
When this review was written, purchaing 1 bottle of Ageless Male was $49.95 and $39.95 if becoming a “super saver” (this may be where they auto ship people a bottle on a regular basis). Ageless male can also be purchased at Vitamin Shoppe and local drug storesHere's Ageless Male on Amazon too
Ageless Male vs. MDrive
Mdrive is anoher popular testosterone raising supplement. Mdrive also contains Testofen too as well as other ingredients not found in Ageless Male. At the time this review was created, there were not studies that compared Ageless Male to Mdrive to see which was better.
The Mdrive Review has other information on that product.
Ageless Male vs. Nugenix?
Those investigating natural ways to increase testosterone levels have probaly heard of Nugenix. Like Ageless Male, it's advertised on TV and on
the the web. Nugenix also contains Testofen and other ingredietns not found in either Ageless Male or Mdrive. Further commplicating the issue is that there ar several different types of Nugenix too. So far, no study Im aware of has compared Nugenix to any other testosterone raising supplement.
See the Nugenix review for more on that product.
Ageless Male Side Effects
Based on the ingredients listed, I believe Ageless Male is safe. I'm not aware of any bad side effects from the product. It's important to remember that a testosterone supplement like Ageless Male is likely not going to have the same side effects as taking testosterone itself.
That said, here are a few things to keep in mind if using this or other testosterone booster supplements. This list is not complete:
- With all new supplements start with less than is recommended for the first week to see how you react.
- Fenugreek might lower blood sugar levels. This may be a problem for those with diabetes.
- Stop taking Ageless Male and other supplements at least 2 weeks before having surgery.
- Kids and teenagers should not use fenugreek or Ageless Male. The product is not designed for them.
- Ageless Male is not appropriate for women especially those who are pregnant or breastfeeding.
Those who have any health issues or take any medications are encouraged to speak to their doctor first.
Ageless Male And Hair Loss
Since Ageless Male is touted to raise testosterone levels, some might wonder if that might lead to hair loss as more testosterone is converted to DHT (which is linked to hair loss). Im not aware of any evidence of this. Fenugreek appears to block the enzyme that raises DHT levels (at least partially. See study 2 above).
Does Ageless Male Work?
It's difficult to say. If Ageless Male really works it's effects might be best noticed in men who have low testosterone levels. As for as libido is concerned, this is a complicated issue. Remember lack of erections may be a sign not just of low testosterone levels but heart disease as well.
For those who really want to know, men should get their testosterone levels measured first. Then, try Ageless Male for a month or so and then measure testosterone levels again. That is the best way to know if Ageless Male is really working.
Here is Ageless Male on Amazon for those who want to compare prices.