Plexus Accelerator Plus: Critical Review of Ingredients and Side Effects

The Plexus Slim Accelerator Plus supplement (Accelerator +) is said to have “Synergistic benefits help increase the effectiveness of Plexus Slim.” The product is also claimed to “increase energy”, “suppress appetite” and “speed up weight loss and fat inches.” Sounds good but does it work? Is it safe? Accelerator Plus is a new formula that is significantly different from the original Accelerator formula. It contains new ingredients, some of which I’ve never seen before. Because of this, I will review the Accelerator Plus weight loss supplement according to the research on itself ―if any exists ― as well as its ingredients. By the end of this review, my goal is that you have a better understanding of whether the product lives up to its touted benefits and if you need it. Also see my review of Plexus Boost for more info.


Who Makes Accelerator Plus?

The Accelerator Plus is a product of Plexus WorldWide Inc. which is located in Arizona. I cover

Adapted from

Adapted from

the company and other things in my review of Plexus Slim so do read that for additional information. As of 12/9/13 the Better Business Bureau gives Plexus WorldWide a rating of B+. Check the BBB file as they update ratings regularly.


Accelerator Plus Ingredients

According to the bottle, Plexus Slim Accelerator Plus has the following ingredients:

Niacin (Niacinamide) 20 mg     100% DV
Vitamin B6 30 mg    1500% DV
Vitamin B12 500 mcg   8334% DV
Calcium (Calcium glycinate) 50 mg    5% DV
Chromium (Chromium picolinate) 1.5 mg   1250% DV
Proprietary blend, composed of 950 mg
Yerba mate leaf extract
Hawthorne leaf extract
Green tea leaf extract

Mg=milligrams. Mcg=micrograms.

DV=Daily Value based on a 2000 calorie per day diet

Other ingredients listed. The bottle indicates that the product also contains vegetable capsules and something called NuFlow. NuFlow is an ingredient used to stabilize the powder in the Accelerator and prevent it from clumping. According to its website, it’s a substitute for silicon dioxide.


Accelerator Plus Research

I searched the Plexus Slim website for research on the Accelerator but did not find any. The product website does say that :

“When taken with Plexus Slim, the Accelerator + helps speed up weight loss or helps people overcome weight plateaus.”

But ,they offer no proof that the combination of these products provides any added benefits over Plexus Slim alone. If we go back to the In the non-published clinical trial on Plexus Slim, it appears that the 8 people in the trial did not use the Accelerator but rather only Plexus Slim alone.

Tip. For more on the Plexus Slim clinical trial, see my review of Plexus Slim New Formula.

So, where is the proof that the Accelerator Plus adds any benefits to Plexus Slim alone?

Since the Accelerator Plus supplement appears to have no published peer reviewed studies on it, let’s now analyze the product by its ingredients and see what we can learn. I will show the weight loss research on each ingredient ―with an emphasis on the Accelerator’s proprietary blend ―and in this way, hopefully shed some light what might be going on.

The Vitamins and Minerals

The Accelerator Plus supplement contains these vitamins and minerals:

  • Niacin
  • Vitamin B6
  • B12
  • Calcium
  • Chromium

I don’t believe any of these ingredients contributes significantly to the product. That said, I do want to touch on a couple of the ingredients because they show up a lot in other supplements.

1. Niacin

The form of niacin used in Accelerator Plus is niacinamide. Some people report flushing of the face after taking niacin but niacinamide should not do this.

2. Vitamin B12

The Accelerator Plus supplement has 500 mcg of   this vitamin which is 8334% more than people need to be healthy. In some circles vitamin B12 is thought to help people lose weight ― despite any proof that it does. For more info see my review on Vitamin B12 and weight loss.

Vitamin B12 might also be in found in weight loss supplements because some medications that treat diabetes can deplete B12 levels. Since people who take weight loss products may have type II diabetes and take these types of medications, on the surface, it might seem logical to add vitamin B12. That said, since we store vitamin B12, it often a couple of years for a deficiency to show up.

While lack of B12 may make people feel tired (due to anemia), vitamin B12 supplements does not boost energy levels in those who are not lacking in this nutrient.

2. Chromium Picolinate

Chromium is often used in weight loss supplements because of some evidence that it might help insulin work better, and in this way help reduce blood sugar levels.  This is actually somewhat controversial because not all research supports that chromium works. For example, in this 2012 study, insulin was less efficient (in other words, insulin didn’t work as well) in those who received chromium picolinate.

For more information, see my review of Chromium Picolinate and Weight loss.

Accelerator Plus Proprietary Blend

I will list the relevant weight loss research on the ingredients in the proprietary blend in order as they appear on the Accelerator Plus label. This is because ingredients are often listed in order of abundance. In other words, since yerba mate is the first ingredient in the list, the Accelerator Plus likely contains the most of this and the least green tea extract, since this ingredient is listed last.


Yerba Mate

It’s scientific name is Ilex paraguariensis. In some studies it’s also called “yerbe mate.” I searched the national library of medicine for:

  • “Yerba mate and weight loss”

Most of the studies I saw involved giving yerba mate to lab rats or mice. Since I’m not big fan of mice or rat studies as the sole basis for the use of supplements, I’ll only briefly list them here:


What about people? What I didn’t see were any human studies showing that herba mate helped people lose weight. What’s up with that? Herba mate contains caffeine and this may be why it’s in Accelerator Plus.

In this 2001 study titled, Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients, a solution containing yerba mate, guarana and Damiana, was noted to help people lose weight. But this study isn’t relevant to our discussion because it involved the use of other herbs that are not found in Accelerator Plus.


This is a phytochemical that is also a heart stimulant. It is also sometimes called Norcoclaurine.  I searched the National Library of Medicine for:

  • Higenamine and weight loss
  • Higenamine obesity
  • Higenamine metabolism

I cannot locate any human studies on higenamine ―alone―and weight loss.

I did find a 2013 study titled Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acids and energy expenditure in human subjects. In this study,  researchers noted that a supplement that contained higenamine, given to 16 healthy people, increased calorie burning and the amount of fat being used for fuel.

While this is an interesting study, the supplement used also contained caffeine and yohimbe. Since Accelerator Plus does not contain yohimbe, this study is not relevant.

Tip. For more on yohimbe, see my review of the male sex supplement Androzene.

Another reason why I don’t feel the study is relevant is because the people tested were “healthy” and in their 20s. What about people who are not healthy and older?


Hordenine is a phytochemical that comes from barley. It might also be listed in supplements by its scientific name Hordeum vulgare. Hordenine is a compound that has a stimulating effect in the body. Technically compounds like this are called sympathomemetic because they mimic the effects of  adrenaline. This means that hordenine appears to have some stimulant properties. How much this effect might be in people I don’t know.

In an attempt to determine if hordenine helped weight loss, I searched the National Library of Medicine for these terms:

  • Hordenine obesity
  • Hordenine weight loss
  • Hordeum vulgare weight loss
  • Hordeum vulgare obesity

I found no studies that specifically tested hordenine to see if it helped weight loss in either humans or lab animals. Granted, lack of evidence does not necessarily mean something doesn’t work, but it makes me wonder if hordenine was chosen to be an ingredient in Accelerator Plus specifically because of its alleged stimulant properties?



The scientific name for this herb is Crataegus monogyna. Accelerator Plus actually lists “hawthron leaf extract” as an ingredient, but they don’t tell us what extract of the hawthorn leaf they use.  That makes evaluating this herb difficult because different extract might have different effects.

Hawthorn is said to make the heart pump better and because of this, in the past, the herb was used in some settings to help, a serious medical condition called congestive heart failure.  How much it helps is open to debate. I also want to point out that at least one study I found noted hawthorn appeared to make heart problems worse.

Warning: Do not self medicate with hawthorn if you have heart problems. Speak to your doctor first. See the side effects section for more information on hawthorn.

While there is no evidence that hawthorn helps weight loss, because of its effects on heart pumping, I speculate that the idea behind why this herb is in Accelerator Plus is for this reason:

A heart that pumps more blood also pumps more oxygen and nutrients to tissues and organs, in the hopes that this will give people more energy.

This is my wild guess given the premise of what Accelerator Plus is supposed to do.


To the PS Ambassadors: can you please leave a comment and give me a reason why hawthorn is in the Accelerator Plus? Other than my speculation, I can’t find a good reason.

I’ve seen hawthorn in other supplements I’ve looked at before such as:

I’ve also written a review of Hawthron as well.



The scientific name for this is 5-hydroxytryptophan. As the name suggests, 5 HTP is derived from tryptophan, a non-essential amino acid that we naturally make every day. 5 HTP helps us make a brain chemical called serotonin. Elevated serotonin levels appear to improve mood as well as reduce appetite.

In fact, some weight loss drugs such as Belviq, and the now banned drug, sibutramine, function by raising serotonin levels.


Having said that,  there is some evidence that 5 HTP might help weight loss in people. For example, in a small 1998 study titled Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients, 750 mg of 5HTP a day for 2 weeks, lost weight and reduced their intake of carbs and fats.


These results were somewhat similar to a small 1992 study involving 20 overweight women, where 900 mg of 5 HTP for 12 weeks resulted in weight loss and carb intake.


In a 1989 study titled, The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects, 19 women were given 5 HTP or a placebo for five weeks. In this study 5 HTP caused the women to lose weight and eat less food. The amount of 5 HTP used in this study was 8 mg per kilogram of body weight.

Tip. A kilogram is 2.2 pounds. So, for a 200 pound person in this study, this would equal 200 / 2.2 =91 kg and 91 kg x 8 mg = 727 mg per day.


How much 5HTP is in Accelerator Plus? They don’t tell us but I’m guessing it is less than used in these three studies. I say this because the entire proprietary blend of all the ingredients in Accelerator Plus only adds up to 950 mg, and 5HTP is near the bottom of the ingredients list. This says to me that there is probably little 5HTP in Accelerator Plus. Maybe less would work just as well, I don’t know?

For those who are interested and want to compare prices, here is a 5 HTP supplement on Amazon that generally gets high marks from people.


Green Tea Leaf Extract

Green tea contains many compounds and we are not told what extract of the green tea leaf Accelerator Plus contains. Could the extract used by caffeine? Green tea also contains other compounds such as theobromine and Theophylline which have some structural similarities to caffeine. Ultimately, I don’t know, so If anyone has the answer, please leave a comment and let me know.

Stimulant Ingredients in Accelerator Plus

  • Herba mate
  • Higenamine
  • Hordenine (maybe)
  • Caffeine (if it contains caffeine)


Summary of Ingredient Actions

Looking at the ingredients in the proprietary blend as whole, they seem to fall into two categories:

  • Those that act as stimulants
  • Those that might raise serotonin levels

This is somewhat analogous to how some weight loss drugs work are supposed to work. That said, how effective the combination of ingredients in Accelerator Plus would be, I can’t say, since there doesn’t appear to be any published research on the product.


Ingredients With The Most Evidence

Based on the research I could locate, it appears that 5 HTP has the most human evidence that it might help some people lose weight. That’s not to say 5 HTP is a slam dunk because there aren’t a lot of studies, but there is more in support of 5 HTP than the other ingredients. Theoretically, is possible that weight loss benefits might be greater with the combination of ingredients in Accelerator Plus but without proof, it’s hard to say.

For those who want to compare prices, here is 5 HTP on Amazon


Accelerator Plus and Plexus Slim: Better Together?

On the product website the claim is made that Plexus Accelerator Plus has “Synergistic benefits help increase the effectiveness of Plexus Slim.” But the company provides no proof that this is true. Even in the clinical study used to tout the effectiveness of Plexus Slim, there is no mention of any Accelerator used. Theoretically, if the Plexus Accelerator plus does what the company says it will do, there may be an enhanced effect, but until somebody tests the combination against plexus slim alone, it’s anyone’s guess.


Accelerator Plus vs. The Old Accelerator

Remember, Accelerator Plus is the new version of Plexus Accelerator. I cover the ingredients in the original Plexus Accelerator, in my review of Plexus Slim, so do read that for additional information, but here is a quick side-by-side comparison of the old Accelerator vs. the new Plexus Accelerator Plus for those who were curious:


Accelerator Plus ingredients

Old Accelerator formula

Niacin (Niacinamide) Calcium
Vitamin B6 Magnesium
Vitamin B12 Dark chocolate
Calcium Natural caffeine
Chromium picolinate Green tea extract
Yerba mate leaf extract Vanadium cheleate
Higenamine B-Phenylethylamine HCl
Hordenine Gerana X*
Green tea leaf extract

*See my review of Plexus Slim for more about the ingredient called Gerana X

Comparing both old and new products side-by-side, it appears that the only ingredients that the Accelerator + has in common with the old formula are:

  • Green tea
  • Calcium


Accelerator Plus Side Effects

If you are have experienced any side effects from Accelerator Plus please leave a comment so others can benefit.

The Plexus Slim website does say this about the Accelerator Plus:

Warnings: Plexus Worldwide, Inc. products are not intended for expectant or nursing mothers. If you have a heart condition, high blood pressure or any other cardiovascular condition, please consult with a physician before taking this product. Not intended for children under the age of 18. Avoid taking Plexus Worldwide, Inc. products with cold medicines containing pseudoephedrine, ephedrine, PPA, or products containing high amounts of caffeine. Before starting this or any other supplementation, consult a physician first. If unpleasant effects occur, discontinue use.


Given the ingredients in the product, I think these cautions are appropriate. Here is a short list of theoretical issues that occurred to me as I was writing this review.


Since herba mate contains caffeine, it might increase blood pressure in some people. In a 2013 review of herba mate and cancer research studies titled Maté consumption and the risk of esophageal squamous cell carcinoma: a meta-analysis, researchers noted that consumption of herba mate was associated with cancer of the esophagus. Some research suggests that  smokers who use herba mate may be at a greater risk than non-smokers. Would taking capsules that contained herba mate for short periods of time do the same thing? I don’t know.

Higenamine can accelerate heart rate ,and as far as I can tell, has not been adequately tested in humans for safety. For more info see this review on higenamine at WebMd.


Stop all supplements at least 2 weeks before having surgery. Many supplements can increase bleeding which is dangerous if you are having surgery. Do not use the product while pregnant or breast feeding.


There is some evidence that hordenine might cause a false positive test result for opiate use.  Because hordenine can have a stimulating effect, theoretically, it might increase heart rate and blood pressure, although I can’t find any evidence that it does.


Hawthorn, can interact with high blood pressure medications. . I believe people who have:

  • Heart problems
  • Blood pressure problems
  • Kidney problems
  • Liver problems

or who take medications for these health issues, should speak to their doctor before taking hawthron or supplements that contain this herb. Since many of those who take this Plexus Slim supplements may be overweight, it’s possible they may have some of these health problems.


Some people have reported heart palpitations and dizziness after taking the hawthorn. Hawthron can also interact with many types of medications such as those used to treat high blood pressure. Because Plexus Slim does not tell us the hawthron extract they use, or how much is in the Accelerator Plus, it’s impossible to know what side effects ―if any ―people might experience.

5 HTP helps make the hormone melatonin, which can make people sleepy. Having said that, would the Accelerator Plus make people feel tired by its raising of melatonin? I’m not sure. If you read through the comments, there have been people who said they felt sleepy after taking Accelerator Plus.


Because 5 HTP can raise serotonin levels, theoretically it might interact with antidepressant medications that also raise serotonin. This combination might ―in theory ―make serotonin levels go to high and cause a serious condition called serotonin syndrome. Symptoms of this condition can include but are not limited to:

  • Rapid heart rate
  • Elevated blood pressure
  • Vomiting
  • Muscle twitching

For more on this condition see the serotonin syndrome and other 5 HTP research topics review at NYU Medical Center website.


I can’t discuss 5 HTP without mentioning Eosinophilia–myalgia syndrome (EMS), which is a very rare disorder characterized  by debilitating muscle pain and high levels of immune cells called eosinophils. This disorder was big news in the late 1980s because it resulted in the deaths over 30 people. All of these people were taking the amino acid, tryptophan.


Now, while it is still debatable what caused EMS in these people ―tryptophan itself  or a contamination product in the tryptophan ―I mention this because there is speculation ( only speculation and not confirmed fact) that 5 HTP itself may also raise the risk of EMS. Given how many people have taken 5 HTP over the years, I think the risk ―if it really exists ―is pretty low. I mention EMS is not to scare anyone or be controversial, but rather because I felt I would be remiss if I did not mention it.  For more information on EMS, see the EMS Network website.


Does Accelerator Plus Work?

There is no doubt that there are some powerful words and testimonials on the web about how great the Plexus Accelerator Plus is and even the name “Accelerator” implies that the supplement will speed up weight loss and metabolism. That said, I can’t find any good proof that the Plexus Accelerator plus raises metabolic rate in humans or that it causes extra calorie burning or weight loss. If you read the comments below, take note that some say Accelerator Plus doesn’t work. Interestingly some say the same thing about the new Plexus Slim formula also.

Of of all the ingredients in the product, only 5 HTP has any evidence that it works in human. I think this is also the ingredient responsible for making people sleepy, a side effect some have reported. I see no good proof that Plexus Slim works better with the Accelerator Plus than without it. Maybe it does or doesn’t.

For those who are interested and want to read comments by others, here are Plexus products on Amazon if you want to see what others are saying.

 What do you think?


  1. Pete says

    Thanks, Joe. Enjoyed your review of the Plexusslim Accelerator Plus. Obviously, it took a lot of hard work, and I for one, appreciate it.

      • Shannon says

        My sister just tried these pills. :( her heart rate went to 160 and blood pressure dropped so low she had a seizure at work. She only took 1 pill and she is healthy with no allergies. They have a weight loss competition at her job now and then n she just wanted to loose a little weight.

        She works at a doctors office thank god and they helped her flush it out of her system. She just called me tonight and told me a 21 year old girl had a stroke after using these pills as well. Do to confidentiality that’s all she could say.

        They told my sister if she took 2 she could of had a stroke too. I tried to worn people and posted sites like on this stuff and sales people called me a liar and to get my facts straight and there has to be something wrong with my sister not the pill.

    • says

      I want to say thank you for your research!

      I work for the Taylor Hooton Foundation ( and we deliver education programs on the dangers of using dietary supplements and anabolic steroids. I thoroughly enjoyed reading through reviews and supporting documentation.

      I am now well versed on Plexus supplements, it has been brought to my attention a couple times and I was not familiar with the company, products, or product ingredients. Thanks to you and your hard work I can now talk more intelligently about Plexus and have a source to refer people to if they want detailed information on Plexus.

      Thanks again!

      • Joe says

        Damian, you are very welcome. I remember Taylor’s story very well and am glad something positive has come from such a tragedy.

    • Angela says

      I took the Plexus Slim with accelerator before they changed the formula and lost 30 pounds with no side effects. I decided to go back on the program shortly following the reformulation, and on the first dose (2 accelerator pills) I wound up in Emergency Dept with a heart rate of 170 and risk of stroke.

      Luckily I work in a physician’s office and was able to check my stats before I was escorted to the hospital by a co-worker. This product is now dangerous, I have no idea why they would re-formulate something that was working so well.

      • Michael says

        They reformulated because it contained a harmful ingredient, DMAA. And if this company would irresponsibly have ingredients like that in their initial product, it should come as no surprise if they would do it again and again.

      • Gabriela says

        Angela as I was reading your post, why would you take two accelerator pills when it specifically says to take one after breakfast and if needed another one at lunch. I have only the done the 3 day trial. I didn’t feel anything except sleepy after taking the accelerator, but after reading Joe’s review, it makes sense, though I do not take any antidepressants. I am ordering a 30 day supply and will try it for 30 days to see how it does. I will let you know as soon as it comes in and will up date you 30 days after.

        • Angela says

          Hi Gabriela, first of all, I was taking two pills with the last formula, and managed to lose a lot of weight with no side effects. Second, the label states “In the morning take 1-2 capsules orally with one stick pack of Plexus slim per day”.

  2. JackieC says

    Thanks again, Joe, for doing all the hard work for us. I had a bad experience with Plexus Slim and this Accelerator Plus sounds even worse to me. When I asked my doctor about Plexus Slim he just said, “Natural isn’t always safe!” He said he would not be knowledgeable enough about herbal ingredients to tell if they were good or bad.

    He did say that calling Hoodia something else is very bad for people on BP meds. I notice now they call it Hoodia instead of the “natural” name. The person who sold me the product has always preached “no caffeine” for her and I see that both Plexus Slim and the Accelerator have plenty of caffeine in them. Yikes!

    So far for her Plexus products are the be all end all of the universe. She said she does not listen to any negative about these products. Double Yikes! Thank goodness for you website. Keep on keeping on!

    • Joe says

      JackieC, thanks for writing and Id agree with your doctor that natural does not always mean safe. I think I understand what they are trying to get at when they reformulated the Accelerator because as I mentioned the ingredients reminds me of how some weight loss drugs appear to work. I wish they would remove hawthorn from the product. I believe 5 HTP is the “active ingredient” given the research I saw on all the other ingredients. I understand why some PS ambassadors might not want to listen to things that are counter to what they believe. That is their choice.

        • Joe says

          Patrick, Ive heard that complaint before – people felt like they were on speed. While there are stimulants in the product, I didn’t find any that appeared to “look” like speed (methamphetamines). It is possible though that people would feel “reved up” when they took it though.

  3. Pete says


    This article refers to Hordenine being a component of bitter orange. And as stated in your former review of the Old Plexusslim Accelerator which was associated with DMAA, acts like ephedra, or bitter orange which are potent stimulants. We don’t know how much Hordenine is in The New PS Accelerator Plus, but do you feel as more is known about Hordenine,, and it becomes more widely utilized, we may run into the same issues as the Old PS Accelerator.

    • Joe says

      Pete, thanks for that link I missed it in my hodenine research. there appears to be so little known about hordenine that its hard to say either way if it might act like DMAA or not. I think its in the PS accelerator Plus because of a theoretical effect rather than one born out of research. Given the lack of evidence, I personally wish they would take it out of the product until we know more.

  4. Pete says


    One other point to bring to your attention on the link I provided on Hordenine. Under drug testing, high doses of Hordenine has been known to interfere with MORPHINE drug testing kits, and may cause FALSE POSITIVES on morphine in drug testing. One of the dangers of not knowing how much Hordenine is in the New PS Accelerator Plus.

    • Joe says

      Pete, yes that is something people may want to consider if they think they might be having a drug test. I think its only some drug types tests that might be effected but Im not sure.

  5. Denise says

    I am shocked at the difference in the ingredients of the first accelerator to the new formula. Before I read this I knew something was different. The sample packs 3-7day packs have the old accelerator. When you purchase the month supply, your accelerator is in a bottle and the capsules look totally different. Also the bottle says 1-2 a day.

    What I have noticed so far is my appetite is not as suppressed as with the samples. I crave sweets again. Not as bad but still enough to be disappointing. Not sure it’s worth the cost with the Complete overhaul of ingredients. I have read a side by side of the slim yet. Will do shortly.

    • Joe says

      Denise, Do they list different ingredients on the sample packs? I had no idea the sample packs and bottle of Accelerator plus have different ingredients.

    • dmgraham64 says


      I noticed the same thing, only not with the sample packs. I purchased a months supply and felt increased energy, suppressed appetite and lost craving for sweets. In the 1st month, I lost 10 lbs. I also stayed very aware of how I felt. Both of my parents have high blood pressure, and I am very borderline, so I have a blood pressure cuff and monitor my blood pressure frequently.

      I noticed no negative side effects, only positive. Then they changed the formula and all of the positives went out of the window. I gained 4 lbs back, and am craving sweets like there’s no tomorrow (and I never craved them this bad before). I’m going to finish my supply and see if I just needed to get used to it. If no change, then I guess I won’t be purchasing Plexus anymore.

      • Mommy of 4 says

        The original formula was testing positive in UAs it was literally a form of speed. You may gain some weight while your body detoxes the drug.. Like any detox you crave other things like carbs and sweets. I am an ex drug user and the trial pack was too similar to meth side effects that I couldn’t take it. When I found out they changed it due to people having hot UAs I was actually relieved I stopped. It can take months to detox naturally – be patient :)

      • Terri says

        I am glad I came across this site and the comments. I too took the original accelerator for 3 months and lost 15 lbs. At the beginning of January I started the new accelerator plus. I am hungry all day and I crave, crave, crave sweets. I have gained 5-7 lbs back since Christmas. I could not figure out why these cravings were so bad. I guess I am not alone!

        • Joe says

          Terri, I’m glad you were able to find my review and I appreciate your feedback on how the new formula is working. I’m curious, have you mentioned how the new accelerator isn’t working to your PS ambassador or to the company? If yes, what did they say?

          Please share my site with your friends so they know I’m out there. I currently have over 160 reviews on a variety of supplements with more coming.

          • Bart Mixon says

            While I’m as frustrated as anyone by the way the new accelerator has been handled, accelerator is not for long term use. If you took it 3 months then you had already taken it longer than it was intended. Plexus Slim is the only product designed for long term use. They are very clear about this

      • Gabriela says

        Bart, thanks for pointing that out. My ambassador told me to take it for the first 30 days then stop but may take after 30 days twice a week for maintenance but to make sure I stop for 30 days after 30 days of taking it..sorry too confusing..basically, she told me the body gets use to something to where it will not work as well, plus she said is to help you lose the weight at the beginning and not intended for a long term use.

        What she did recommend is that I take the Plexus Slim every day and she has many followers in Facebook that swear by this product(Plexus Slim). She explain to me that Plexus Slim is more for health benefits and not so much for losing weight but more for maintaining it.

        She herself takes religiously and has been doing so for a year and has customers that have been doing the same. She did ask me if I was taking any medications. She stated some medications can have an adverse reaction. I am glad she is one of the good ambassadors that actually explains things to me and was not trying to push a product.

        • Joe says

          Gabriela, if I can chime in for a bit, there is no evidence that the body gets used to the accelerator. Id ask your ambassador where shes getting that information – and let me know as Id like to take a look at it. They have significantly changed the accelerator ingredients since my review (I will update it I promise). The plexus is for “health benefits” is something ambassadors only recently started saying. If you look through the comments on my original PS review, you’ll see in the beginning – couple of years ago – people were not saying that. I take it all to be ‘talking points.” Regardless, I do hope it helps you.

          • Gabriela says

            Joe, thanks for replying and love the research you do. I believe the information was more her personal belief. Honestly she spoke more on a personal level than of a sales pitch. As stated, her and her FB followers swear by plexus slim drink as far how the drink makes them feel, the health benefits that they have achieve since taking it and these are not people she can make up, some of these people are my neighbors (which I did not know, they were on this stuff).

            She did advise me of discontinuing it if I had any side effects and to let her know right away. She also advised that Plexus like any other dietary supplement is not for everyone, so not to be discourage is this doesn’t works and to continue looking for the right product. But I figure, I give it a try and see what happens.

          • Michael says

            Gabriela, you state “I am glad she is one of the good ambassadors that actually explains things to me and was not trying to push a product.” Yet you state she tells you to take Plexus Slim every day. That is pushing a product. As Joe mentioned, the human body does not simply accommodate something like a stimulant to where you get used to it. Know what a stimulant is and the harmful effects it has on your body before taking these and any other “supplements”.

            Additionally, just because people on FB “swear by this stuff” does not give any credence to it. I would bet that these folks are also ambassadors who have a vested interest in selling the products. Are we to believe they would put out negative comments? Do your own research. This stuff has been the subject of bans in other countries and the FDA has sent a warning letter to the company over claims it has made.

        • Molly says

          People do get used to stimulants. That’s why drug users have to keep increasing their dose to get the same “high”.

          • Michael says

            You’re absolutely right, Molly. In order to get the same kind of “energy” that these Plexus folks speak about, they will at some point have to increase the amount of stimulant to get the same results. I’m saying that the human body does not simply stay static when stimulants are ingested. There are going to be side effects, whether it is withdrawal-like symptoms or damage when you constantly take them.

            Artificially raising heart rate via stimulants is a very bad way to treat your body. I’m pretty sure that these Plexus ambassadors and their cult followers have zero understanding of what these chemicals do to their system.

    • Joe says

      Hi AnnMarie, DMAA has been very controversial and whether it was in the Plexus Slim Accelerator Im not sure because they used funky/ made up words like Gerana X which some websites say is a reference to geranium oil. Some say geranium is a source of DMAA while others say its not. In my original review of plexus slim (here is the ink):

      I covered the PS accelerator and discussed the DMAA connection and included links about the issue also. I dont feel the new plexus slim accelerator plus has DMAA but it does have stuff that I personally would be cautious of. I dont feel Accelerator Plus is necessary if plexus slim works as well as they say it does.

      Let me know if you have any other questions :)

  6. Lorna andrews says

    I see a lot of information about weight loss, none about migraines or arthritis. I was told this is great for arthritis that causes headaches. Any information in this, thanks

    • Joe says

      Lorna, Ive never seen any evidence that plexus slim accelerator Plus helps migraines or arthritis. That said, there is some evidence that caffeine can help migraines. Accelerator Plus does have caffeine and other stimulants but so too does coffee etc. which is less expensive.

      On the flip side, people sometimes get headaches when they abstain from caffeine after they get used to it. Here is a link that discusses this

      If people lose weight with plexus slim (or anything else), then this reduces stress on joints and reduces joint inflammation. In this way, weight loss can help reduce arthritis pain. If plexus slim reduces body weight, then I can understand how people would report their arthritis feels better. But this is more about weight loss helping arthritis pain rather than plexus slim itself.

      Any other questions, just ask :)

      • says

        I started using the triplex combo this past August, which is the slim drink, probio, and bio cleanse. I started noticing a difference in how I felt in just a week. I no longer have chronic migraines, achy joints, and the chronic fatigue I always felt. My cravings for sweets has also gone away. My brother started taking the pain relief and nerve health support. He’s quadriplegic and suffers from chronic back pain. Many with paralysis suffer from pain and cramping below the site of injury. His pain is reduced and he said the cramping and burning that he had in his legs every morning is gone. I did try the accelerator and by the second day had a hard time getting to sleep so it does rev you up. I stopped taking it because I don’t like something that messes with my sleep pattern.

        • Pete says


          I see where Joe allowed you to mention three products in your little, in my opinion, sales pitch.

          Have you even considered, or thought about this:

          If the products you mentioned delivered the benefits to you, and others, then why doesn’t PS have the research performed to prove it.

          Here’s why. You, and other PS supporters need to read this carefully. 1) They don’t have the money to do the necessary research. (If they believed in their product, they could get a loan or work an agreement with an investor who does have the money. This is a poor excuse for a product if it actually “works.”)

          2) They don’t want to have their product tested. In many cases these products are just common juices and spices and there’s no reason to expect them to do anything medically different than your orange juice or your Cinnamon Toast Crunch. However, as long as they are able to make a reasonable case to a gullible person that their product works, it is to their advantage to never formally test the product as they would be proven wrong. Such a move would end their business instantly.

          This disappointing part is that there are gullible consumers who don’t realize that if the company truly believed its product worked for any medical condition it would likely make billions of dollars. The company should be extremely interested in doing these formal clinical tests as it would mean so much more money for them. Yet, I have never seen an MLM company perform these large scale tests with the goal of getting on the FDA list. It seems that these companies have very low confidence in their product.

          My heart goes out to your brother (if real). Great that he is doing better, but don’t think for a minute it’s a result of PS, or the other products you mentioned. If you do, then go back and the read the GULLIBLE portion of the post again.

          • Michael says


            I’m wondering if this is the person who put up the grotesque pictures of the quadriplegic holding a bottle of Plexus Slim on a website?

          • Pete says


            I never saw the information and picture of a quadriplegic holding up a package of PS, but I am hardly surprised. To bad the FTC, or FDA didn’t get wind of it.

            My response to Debraot’s post:

            QUACKERY exploits the dream of success by drawing numerous people into multilevel marketing (MLM) schemes to market dietary supplements, weight loss products, herbs, and other unproven health product, like PS. The post by Debraot, in my opinion, is just pure old “quackery”. PS relieves pain of a quadriplegic? I thought PS had a pain product!

            Most multilevel companies, like PS that market health products claim that their products can prevent or cure disease. Some companies make therapeutic claims in their product literature, hoping the government won’t act until their customer base is well-established. PS, “guilty”. (FDA letter) Other companies make no claims in their literature but rely on their distributors to supply anecdotes, testimonials, and independently published literature. PS, “guilty” PS distributors usually encourage people to buy their products and then give credit to the product if the person “feels better”. PS, “guilty”. In my opinion, this what Debraot witnessed.

            After all the issues above that concerns PS, Debraot wants us to believe her. There again, where is the proof of PS helping her quadriplegic brother

            Americans waste a billion or more dollars each year on multilevel health product, like PS. Those that have nutritional value (such as vitamins and low-cholesterol foods) are without fail overpriced and generally useless as well. The products promoted as remedies are phony, unproven, or intended for conditions that are unsuitable for self-medication. Also, the people who distribute multilevel products are not qualified to give health advice. One more time, PS, guilty”.

            Government actions against multilevel organizations have not been energetic. These companies are left alone unless their advertising is so flagrant and their sales volume so great that a regulatory agency is obliged to intercede. (PS FDA letter) Even then, few agency interventions have much of an impact once a company is well established.

          • says

            No I am not the person who put up that picture. And yes my brother is real. Do the research on the New Zealand Green Lipped mussel which is the main ingredient in the pain relief capsules. My brother does not drink the slim. He only uses the pain relief and nerve health support products.

    • Kathy says

      Lorna, I began using Plexus to see if I could achieve some relief of the pain of arthritis in my neck. It was causing me pretty severe headaches from my neck pain. I refuse to take prescription medications as far as possible, but I had gotten to the point I was taking an 800 mg Motrin every day, sometimes twice, for the pain. I read a lot of customer reviews, specifically searching for arthritis. I noticed a huge improvement within a week of beginning Slim. I’ve been using the product for a year now and my neck still feels so much better.

      • Pete says


        Whatever the case, I am glad your brother is doing better. But, I do have a question about the picture. Are you telling us that you did not know the picture of your brother holding up a bottle of PS existed, or the other party who may have posted it.? Uhmmm!! A picture promoting a product at the expense of someone’s illness is about the sleaziest thing I can think of at this moment. Especially, PS trash!

  7. shannon says

    Joe, thanks for all your hard work. It is great info. While i agree with everyone here that diet and exercise are the key to weight loss and Plexus is not some magic potion. It is starting to help me with cravings and appetite control. Willpower is not as easy to come by with 4 kids under 4 and little sleep. So that is the benefit of Plexus to me. I am doing the Plexus combo and the only time i had any side affects was when i very ignorantly took two accelerator at the same time. About 30 mins jtdp i thought i was going to collapse or was having a heart attack.
    Once i laid down and slowed my body all was fine again. So basically two a day does not mean at the same time.

  8. Bart Mixon says

    I have been taking plexus/accelerator since last april. Lost 57 pounds. It was a life saver for me. Unlike some other plexus haters I have seen post on your reviews I actually appreciate them. You seem to be reasonably fair and factual. The old saying about something being greater than the sum of its parts may apply to Plexus. All I do know is at the age of 42 I have never been able to lose weight no matter what. For the first time since childhood my weight has gone down rather than up.

    I am not happy with the company. They refuse to say why they changed the formula. I have asked if an ingredient became impossible to get, to cost ineffective or illegal. They only reply it has something to do with an ingredient but won’t say which one or why.

    I can’t take the new accelerator. I am on an anti depressant. I will not risk the possible side effects. I still take the Plexus and still feel great. But I have not been happy with they way they handled the change over. As if the new product was new because it was better, not saying it was new because for some reason they couldn’t manufacture or sell the old.

    I am not speaking bad about Plexus. It gets my highest praise. It has changed my life. But I stand by my observations mentioned above.

      • Melissa says

        Bart, why do you say “I can’t take the new accelerator. I am on an anti depressant. I will not risk the possible side effects.”? Are there disclaimers somewhere that mention that?

    • Pete says


      57 lbs. GONE!! That is fantastic, keep it up. As Joe has mentioned in his review of the new PS Accelerator, the formulation changed because of controversy of DMAA (Geranax) that was in the old Accelerator. It was banned in the US.

      Who knows why the formulation of the PS was changed. To my understanding the company was having success with the old. You are an example of that. Even at that, Joe, in his review of the new PS, states that the changes most probably did not make PS a better product. As you see in the review, some of the changes are the same ingredient, just utilizing a different name.

  9. Sherry Owens says

    Thank you for your extensive research. I’ve seen several testimonies with positive results. I wanted to look at the ingredients, the pros and cons so that I can make an informed decision. I certainly will be checking with my doctor before I make my final decision.

    • Joe says

      Amy, some anti depressant medications alter seritonin levels. The 5 HTP ingredient in the accelerator might also raise serotonin levels. this might cause a condition called serotonin syndrome. Since I’m I’m not aware of any research of Plexus Slim Accelerator Plus and how it interacts with antidepressants (or any other medications either) so I felt this was worth mentioning. Im not aware of the accelerator being an issue for those with antidepressants but I feel its best to show the ingredients to your doctor if you take antidepressants just to be on the safe side.

  10. Lisa says

    Donna, your friend is most likely talking about plexus nerve pills. Plexus world wide carry other products as well as slim and accelerator plus.

      • Penny says

        It is NOT a nerve pill…. It is an all natural nerve health. Here is a link to the ingerd. in it

        As far as the New Acc. I am highly disappointed in the difference. I too gained weight after switching to the new accl. There is a BIG difference and it has effect sells because the customers are not seeing the results that past customers saw.

        • Joe says

          Penny, I just looked at the PS Fast Relieve product in the link you showed. Question. Didn’t the fast relief formula used to have green lipped mussel extract?

          Looking at the ingredients I can tell you there is nothing special in the product to promote nerve growth (as an aside that claim “Promotes nerve growth” I think is pretty specific and may get them in trouble withe FDA which forbids specific claims about supplements)

          My instinct is that the product is being marketed to those who have diabetes- related nerve problems. This is called peripheral neropathy. There is some research on Alpha lipoic acid and peripheral neropathy and this is likely why its in PS Fast Relief. if it works, I think its the alpha lipoic acid that is the active ingredient.

  11. Patty says

    For the lady with arthritis … I could not lift my shoulders up enough to shave under them… One month of Cat’s Claw Root formula I could lift my arms over my head the first time in two years!! My brother-in-law with 16 years of Lupus swears by it. I know this is off the subject but hopefully will help.

    I ordered the Plexis slim and accelerator tonight (a male friend of mine is an ambassador who lost 45 pounds) I have put on 20 pounds in two months due to a drug for allergies that works like the poison prednisone (I had no idea!!!) prednisone weight gain is the worst!!! I gained 11 pounds in 4 days which took me FOUR MONTHS to take off so I refuse to take it now. I had a gastric bypass in 2004 and lost 100 pounds so I watch for any weight gain and have successfully kept my weight at a steady 125/130 range since my goal until THIS!!

    I just can’t seem to get off a pound now. (Side note in my experience only people with pear shapes do well with the gastric bypass…apple shapes seem to gain the weight back and then some). Anyway I’m going to give the slim plexus a month and ill try to report back for those like me who may be putting weight on due to prednisone type drugs (look out for those allergy meds!!! Do your homework!! I wish I had as one woman said the drug I was taking made her eat like a Clydesdale! I didn’t really eat much more but was hungry all the time and still gained!!! Grrr!)

    Sorry this was so long!

    • Bert says

      I have lost over 60 lbs with Plexus. I really hope you see results but I have worked with over 250 customers. My experience has been that people with weight problems due to medications don’t usually see success. You have causes of weight gain that the ingredients of plexus do not address. I do wish you luck though!

  12. Jenni says

    I have a friend who just became an Ambassador and is trying to get me started on Plexus Slim and the Accelerator Plus combo. I have a few health issues and am on a number of medications as a result. My fear was if Plexus Slim had any ingredients that would increase Serotonin levels.

    I have had Serotonin Syndrome before; it came on after starting Reliv, an all natural supplement, and DO NOT want to ever experience that again.

    Thank you for your research; I now know I will not be starting Plexus Slim and I can refer her to your research.

    • Joe says

      Jenni, sorry that you got Serotonin Syndrome and glad you are better now. I think more people should be aware of this condition.

    • Sarah says

      I was just curious how much Reliv you were taking. I’m researching Reliv and trying to keep a notebook of things. Was it after you’re first dose? Was it Classic or Now or something else? And how many scoops? Thank you!

        • Sarah says

          If you go to and click products at the top of the page it brings up links to individual product pages. Under the initial description an picture there’s a link that says “view nutritional panel” and it brings it all up in a pdf. :) Here’s the link to Classic:

          I’ve been trying to decide whether to take it or not. Some of the testimonials are crazy, but if you think about it as just giving your body the nutrition it needs in a way that it can utilize it effectively I guess it isn’t really that surprising. Great nutrition can do amazing things. It seems like the people who benefit the most are people with autoimmune diseases that have tried everything else, and older people who are already getting health problems and general pains and were previously on a lot of prescription meds. It seems like some people only try it out for a few weeks and don’t notice anything, but all the reps INSIST on you taking it consistently for at least a month before you give up. But every body is different and I’m sure it doesn’t do much for some people.

          The big thing that made me hesitant to try it was that most of their products are soy-based. Everyone on the internet says soy is a very very bad thing. So I decided to do some personal research instead of just taking all those popular blogs at face-value. First of all, EVERYONE agrees that GMO soy is very bad, and Reliv grows all their own soy and makes sure that none of it is GMO. So that’s good.

          The bigger thing is that it is pretty much taken for FACT in most circles that the phytoestrogens in soy are huge hormone disruptors and cause all sorts of cancers. Turns out those early studies that scared people about cancer were using rats, and they now know that different species utilize the phytoestrogens differently, and in recent studies soy has actually had a mildly beneficial effect on breast cancer remission rates!

          And one of the ways it DOES help people with hormone problems is because some parts of it CAN act like estrogen, and actually blocks excessive estrogen from causing damage. More recent studies have shown really great results concerning cholesterol, inflammation, and reducing the risks for other cancers like prostate cancer.

          So in the past, studies have been confusing and yielded mixed results, but recent studies seem to be pretty darn positive. I mean, they still need to do more studies and aren’t sure about how much is dependent on the dose or the effect of genetics (race), and I still wouldn’t use soy infant formula if I had other options, and I’m sure there are people with other stuff going on that makes them unable to metabolize soy properly, but I think for most people the benefits WAY outweigh the risks!

          So I’m gonna give it a try. I ordered some last night for my mom and I, and I’ll let you know in a month or two how it goes. :)

          • Joe says

            Sarah, thanks for the link. Ive added the product to my list of things to take a look at. Yes, do let me know what happens in a month or so.

        • Sarah says

          Oh and I forgot to say that one study Reliv recently did (the founder is some big important scientist guy) showed that their soy products worked as well as (maybe better than? I can’t remember) statin drugs without all the awful risks and side effects. :)

          • Joe says

            Sarah, thanks for that info. I will definitely take a look at their study when I circle back to review it.

  13. Linn says

    I tried the plexus slim and accelerator. I have type 2 diabetics, but don’t take meds for it. The accelerator made me feel funny… I could feel my heart beating, which probably meant it was racing. I quit the accelerator and tried just the slim for 2 more weeks. Too gassy for me, made me a little bloated feeling. I’m afraid there’s no sub for eating right in the first place!

  14. Sally says

    I have been taking Plexus slim and the accelerator for over a year. I lost 35 pounds! I started taking the new Plexus slim and accelerator in January and I have gained 10 pounds!! I crave sweets and am constantly hungry. The accelerator also makes me very sleepy. This is very depressing. The plexus company will lose a lot of money with the new formula because IT DOESN’T WORK!!!

    • Joe says

      Sally, I think you are the 2nd or third person to say the new accelerator plus makes you sleepy. That’s so odd…Im guessing its because of the 5 HTP in the product.

      • Lisa says

        I have taken the new Accelarator Plus for two days. I have been drowsy the past two mornings within an hour. I take 2 on a full stomach with a Plexus Slim. I read your comments that there may be a melatonin connection, interesting.

  15. Annabelle says

    I have been on PS and accelerator combo for about a month and 1/2. I then added their cleanse and probio5. I think it has been pretty nice. I’m a working school teacher and mother of 2 under 4 years of age. I have enjoyed the effects. I am running and/or exercising again every other night. I am thinking of dropping the accelerator.

    I had worked my way up to 2 accelerators, at a time. I do get heart palpitations when taking stimulants, but I haven’t had any with this. I have lost about 10-15 pounds. However, I had been having RA flare ups and I haven’t had any since being on the PS product. I have backed off on the accelerator.

    I’m not taking any now, and I am still okay. I am not a big caffeine person, but I have a cup of coffee in the morning. I am curious to continue following this informational site!! Thank you for presenting the facts! I really appreciate it.

  16. Worried says

    I ordered the 7 day trial combo pack and was feeling pretty good with it and lost 2 lbs. So I decided to do the 30 days. Something was definitely not the same! I am fine with the plexus slim however the accelerator Made me feel like I was having a heart attack!!

    My heart was beating so hard I felt like it was gonna pound out of my chest, I started shaking and sweating. Will NEVER take the accelerator again! Please note I have no health problems am 40 years old and am not sensitive to caffeine. Something in them is NOT SAFE!!!

  17. EJ says

    I started taking the new Accelerator Plus and Pink Drink and after 3 months, I have lost absolutely nothing! I am hungrier than ever. Also, I had a VERY hard time sleeping at night when taking the Accelerator Plus. It was horrible! I didn’t see anything positive out of it so I’m done!

  18. Mary Moon says

    I started taking the Plexus Slim/Accelerator combo March 1, 2014. I am a type 2 diabetic on metformin, glimiperide and Bydureon….I could not get my blood sugar readings under 200! As of the end of March I have lost 31 pounds and my blood sugar average is 96! Life saving numbers! I have more energy, sleep better, and believe this product is adding quality years to my life. I am also on Prozac and have not had any side effects.

  19. Amy R says

    I have been on the accelerator and plexus slim for 3 days. I want to lose weight but I was mainly going for the entire energy thing. I should have known better. I couldn’t keep my eyes open with either. Part of my problem, is I tend to have low blood sugar. I can’t eat high carb meals or a lot of sugar because it drops my blood sugar then raises it back up.

    I was also extremely nauseated, to the point it felt like morning sickness. As soon as I stopped taking it, that went away. I also had cramping in my abdomen. I will admit I lost 3 pounds in those 3 days, but I’m pretty sure it will come right back on if I’m not careful because I could barely eat anything because I was so nauseated.

    • Pat Smith says

      Please check for diabetes. Low blood sugar is the result (not cause) of high blood sugar. You need to look at your diet carefully.

      • Amy R says

        Actually it’s not. Some people actually have low blood sugar. I’ve been checked by my doctor, and an endocrinologist. My pancreas actually secretes too much insulin in response to large meals and sugar.

        Unfortunately this may lead to diabetes in the future for me, and I know this. Low blood sugar occurs in diabetes due to a side effect of the medication they are taking. Sometimes if they are on a high dose or don’t eat enough, the medication lowers their blood sugar too much and causes low blood sugar.

  20. anonymous says

    Hello! I started the accelerator about 3 weeks ago. I’m healthy, I have been working out for 2 years. I tried this product to help lose my last 15 pounds. I’m 26. The first day I tried it I thought I was having a heart attack. I didn’t link the product to my symptoms and tried it again the 2nd day. I thought maybe after a couple weeks my symptoms would stop. It hasnt.

    I have lost 4 to 6 pounds. But I’m not sure if it’s directly correlated to this product. I am anemic and around the same time I started the he product I found out so started taking iron, stress b complex along with a probiotic. In addition I started taking an adrenal supplement. So all of these could be playing a role in weight loss.

  21. anonymous says

    Hi I was wondering if you have references for the statements you’ve made against this Plexus product. I am interested in reading more in depth about it. Thanks!

    • Joe says

      Anonymous, I’ve linked to references in my review so you can check them out. If you have specific questions I can try to address them here also.

  22. RN in training says

    Just A Note That Niacin, While Natural, Opens Your Blood Vessels. As Well As The Vitamin Bs People With Bleeding Disorders Should Not Take Plexus Ever! I Have A Bleeding Disorder And While I Have A Mild Form My Hematologist Says I Shouldn’t Take Things That Open Up My Blood Vessels.

    Im Not Sure What Niacin They Use But You Have To Do Your Research As Most Don’t Work As Well As Pure Niacin Alone. Niacin Also Causes Liver Damage. The Only Healthy Way To Lose Weight Is Eating Healthy And Exercise.

    Once You Go Off Thus Product You Will Most Likely Gain All Your Weight Back And Then Some.

    • Joe says

      RN, good points. My rule about supplements is “when in doubt, assume its a blood thinner until proven other wise.” A lot of things (vitamin E, glucosamine, fish oil etc) have blood thinning properties.

    • Rebecca says

      How do you eat “healthy”. Everything contains something that’s bad for you! It’s mind blowing just trying to figure it all out. You have to be a pharmacist or nutritionist. Ugg!

      • says

        You can speak to a nutritionist or dietitian or even take a nutrition course online at your local community college. Online research from reliable sources helps. Many nutritionists and dietitians have blogs you can read or books.

        • Michael says

          Alyssa, those are great suggestions. Sensible and logical. The issue with people who sell or jump on the Plexus cult train is that they do not want to invest any time or effort into doing things sensibly or logically. They simply want it right now. They want to mix a powder, pop a pill, and be on their merry way. They do not have even a basic understanding of how the human metabolism works, they simply buy into what they hear at an ambassador meeting or what they see on Facebook.

          What is more attractive to these kinds of folks, spending time and educating themselves about how to eat sensibly and exercise or taking a selfie while posting “rockin’ the pink drink this morning!” for all of their friends to “like”? It is much easier to turn off your brain and blindly follow the allure of miracle results (unsubstantiated) than it is to do some true investment in one’s health.

  23. CS says

    I took the original plexus slim and accelerator and lost 37 lbs in about a year. The weight didn’t come off quickly, but Plexus allowed me to keep it off. I didn’t exercise much and I pretty much ate what I wanted, but I could eat a bite of something and I was full. I had no cravings. I loved it.

    The new formula doesn’t work for me at all. It doesn’t stop the cravings, it doesn’t make me feel satisfied, and I stay bloated. The old formula worked so well! I hate that they changed it.

    • Joe says

      CS, I would not be at all surprised if they changed the formula if what Im reading here is any indication.

    • Anna says

      Sounds like a new product is in the works!! It is already getting great reviews from the ambassadors!!

      • Joe says

        Be on the look out for my review. I know what’s in it. As soon as it has an official name Ill release my review.

    • Twinmom says

      I agree with CS. I started taking PS and the original Accelerator and lost 20 pounds in 2 months. No cravings at all and easily satisfied with much less food. I LOVED it!! I have ordered 2 more months worth and it is horrible. All I crave are sweets and my appetite is not suppressed at all like the original was doing. Not sure if I’ll order any more Plexus. They had better get back to the original or something with the same benefits or they will be out of business sooner than later.

      • CS says

        Same here! I have never craved sweets the way I craved them when I started taking the new formula..I had to quit taking it.

  24. Rebecca says

    When is this magic weight loss supposed to begin? I have been on Plexus Slim and the Accelerator for 2 weeks now and have not lost any weight and my heart feels like a giant is squeezing the life out of me.

    • Joe says

      Rebecca, STOP TAKING Plexus slim if you feel like your heart is squeezing together! I’m VERY uncomfortable with any squeezing heart pains. People having heart attacks often report it feeling like squeezing pains. Some say it feels like an elephant sitting on the chest. I dont know if that’s whats happening to you but I’d fell better if you just got off all of it. Its not working, so why keep doing it?

      As an aside, I’m analyzing the new plexus product right now (the one they call THBV2) and I can tell you that I do not recommend it either. It contains the same ingredient as in the accelerator plus – higenamine. I think higenamine is one of the reasons you are feeling squeezing pains. I’m not comfortable with higenamine.

      Regardless of all of this Rebecca, no weight loss is worth feeling the way you are describing. Since you are not losing any weight, its not worth it. Rebecca, I just want you to be safe.

      • carriesterma says

        I agree with Joe. Stop taking this product. I have read dozens of people stating they are having issues like this and rapid heart beat … My suggestion: contact Med Watch 800-332-1088 or the consumer complaint coordinator in your state. A list of the coordinators can be found on the FDA website.

        • Anna says

          Please stop taking the accelerator+. According to the information that I have found, it would be the problem, not the slim. The accelerator+ works for me. I have no side effects from it, but I have hears others say differently.

          I have tried the newer product that has been released for the ambassador level customers, it doesn’t work for me. I am starting to believe that both work very differently inside different bodies.

          I didn’t like the way the newest version made me feel and I had more cravings. I think the important thing is to listen to your body. You don’t have to take anything to supplement your weight loss, but if you are feeling bad, definitely drop the accelerator+.

          I agree with Joe too, you do not need to continue with it, if it makes your heart feel bad.

  25. Megan says

    Its nice to see that I’m not the only one experiencing these side effects from the accelerator +. I have spoken with my up line about it and all of them say it is just me.

    My story is similar to many of the other posting on this site. I’m 28, healthy and not on any medications. I Started out with the original accelerator and slim and it worked great, I lost 20lb in 3 weeks, felt good, no food or sugar cravings, I was even exercising again.

    Then the new accelerator came out. The first day I took 2 pills because that is what I was taking with the original accelerator. What a mistake, 45 min in my heart started beating so hard I could feel it in my chest and all over my body.

    Then it began beating faster and faster and I couldn’t get to calm down so I decided to try eating (even though I ate when I took the pills) but when I stood up I started to black out, I thought it may have been from standing up so I tried to give it a minute but it just got worse, then I got jittery and my hands started to shake, I was thinking I might have to go to the hospital. I had my boyfriend make me something to eat and 30 min later my heart was back to normal.

    I was bound and determined to make this work so for the next two weeks I tried everything I could think of to be able to take it. I started with just one pill (same result just minus the black out), tried with food, without food, different foods, different amounts of food, different time of day, mixing into the slim, nothing helped so I stopped taking it.

    I tried contacting Plexus about it but they never responded.

    Now they are coming out with a new product, no ingredients are listed and right now it is only called pre launch product. I was so excited when I saw it, I thought they were finally listening to all the issues people have been having and decided to change the accelerator +.

    I took 1 pill yesterday and its worse, IF YOU HAVE PROBLEMS TAKING THE ACCELERATOR+, DONT TRY THIS NEW PRODUCT. Just like with the accelerator + 45 min in the heart problems started but the jittery feeling got so bad I almost couldn’t walk, then I got cold sweats and started to black out, on my way to sit down I started vomiting, after that I felt a tad better but was really cold, I crawled into bed and just wanted to pass out I was so exhausted but had to go to work. No more Plexus for me thanks.

    • Joe says

      Megan, really sorry that happened to you and I appreciate you taking the time to alert people about this. I believe the many of the side effects people are experiencing with the Accelerator + as well as with the new pre-launch plexus product (THBV2 as they call it for now) are due to ingredient called “higenamine.” Both products contain Higenamine. This ingredient is a stimulant and increases heart rate and blood pressure. This effect may be greater when combined with caffeine (herba mate which is also in THBV2 has caffeine and does green tea also). While I try not to be a “bomb thrower” I’m starting to wonder if higenamine is the new “DMAA” substitute in supplements?

      Because of the lack of human research, I can’t recommend supplements containing Higenamine. Your experiences reinforce my opinion on this.

    • Joe says

      Kelly, I just learned that it has an official name -Plexus Boost. Ill try to get my review posted sometime this week.

  26. April says

    I have been taking Plexus faithfully for 30+ days and have noticed a racing heart, shakes, and I become easily agitated. After speaking with my husband I decided to stop Plexus to see if that was the culprit. I’ve read several of the comments above but not all…I’m curious if this is something others have had problems with.

    Also, today is the first day I have not been on it…I’m wondering when this stuff will be out of my system and I won’t have these symptoms. Any thoughts?!

    • Joe says

      April, yes some people have reported having higher heart rates while on the accelerator. Based on what you stated, I would not recommend using it anymore. I’m honestly not sure how long it takes to get out of your system. I recommend not using any caffeine until you feel better. If you feel worse or you dont feel better soon, I also recommend going to your doctor.

      Also see my review of Plexus Boost as this contains several similar ingredients

      • Rebecca Burton says

        I had that problem too and finally realized that the 5-htp (trytophan) adds too much serotonin because I’m already on an SSRI antidepressant. That causes serotonin syndrome and the racing heart is one of the first signs of that. By the 2nd or 3rd day off of plexus I was feeling much better.

        • Joe says

          Rebecca, glad you are feeling better. 5 HTP is an interesting supplement but I advise people who take antidepressants to speak to a doctor first, because of what you stated.

          • Gabriela says

            Joe, my ambassador is a great person, she make sure to educate me. She herself took the Boost, but she said she did not like the way she felt, so she stop taking it and she does not recommend it to any of her customers but if they still insist she warns them about all the possibilities.

            As stated before she has been on Plexus as well as her followers (facebook) for over a year and they love it and swear by it. She only recommends the accelerator for 30 days and then off, she stated is not for long term use. I took the 3 day trial, I felt very sleepy an hour after taking it, but after reading your review I can blame the 5 HTP, though the only medication I take is Gapatin (something like that).
            I am going to try it for 30 days..let’s hope no funny stuff.

          • Joe says

            Gabriela, I truly do hope plexus helps you. For what its worth I recommend starting any new supplement with less than is recommended for the first week, just to see how you feel and cut back on any potential side effects that might pop up. Hopefully there are none with you.

  27. says

    Questions: RE: LABEL.. perhaps a question elsewhere, but putting it out there anyway for you.. The labeling on the “Accelerator+” states: “Plexus Worldwide, Inc. products are not intended for expectant or nursing mothers. If you have a heart condition, high blood pressure or any other cardiovascular condition, please consult with a physician before taking this product.

    Not intended for children under the age of 18. Avoid taking Plexus Worldwide, Inc. products with cold medicines containing pseudoephedrine, ephedrine, PPA, or products containing high amounts of caffeine.

    Before starting this or any other supplementation, consult a physician first. If unpleasant effects occur, discontinue use. – See more at:

    1) Should this be interpreted as on overall blanket statement for all products they sell?
    2) They have changed their name, so does this even apply?

    3) The people in the “testimonials” were the same people in the testimonials before this product was in the companies hands, so how can they falsely advertise and get away with it. (yes, I contacted bbb)

    • Michael says


      You pose great questions. The problem with this product, and most every other “supplement” is the lack of regulation and standards. Look no further than the recent issue with the Sensa product. These folks were allowed to run commercials that implied if you simply shake this product on your food, you will lose weight.

      After all the catchy jingles and incessant commercials, the FTC finally got around to slapping Sensa with an order to return $26.5 million to consumers for misleading statements.

      In addition to the weak oversight on this industry, the larger concern are the people who actually believe you can sprinkle something on food and magically lose weight. These same people are allowed to hold a driver’s license, vote, and procreate, which is even more frightening.

      Are we to believe that these same people would stop and adhere to warning labels? No, but they sure as heck will fall all over themselves when they see “testimonials” that litter their Facebook page on a daily basis.

      And with the added propaganda of making big bucks for selling this stuff, the lemmings flock in droves.

      I applaud you for contacting the BBB. Maybe that will start the ball rolling on something.

  28. Kylee Reed says

    I used Plexus Slim and Accelrator for 21 days after a friend who is an Ambassador convinced me to do so. My first day I was very anxious and dizzy. I expected there to be side effects since I usually do not drink caffeine. I shrugged it off and after a few days I was fine. I lost 3 pounds in the 21 days and was told by my doctor to stop due to a family history of heart problems and the fact that I take Celexus.

    Now that I am off the product, I am experiencing severe headaches that last all day and do not ease even with medication. I suppose it is from the caffeine withdrawal but no where have I seen this listed as a post-product side effect so I wanted to share.

    • Joe says

      Kylee, I do appreciate you sharing that and hope the headaches go away soon. They shouldn’t last long if it is due to caffeine withdrawal. If they dont get better soon, I think you should go back to your doctor.

  29. Theresa says

    I tried the plexus and accelerator for one week. I ended up with my hands and feet itching so bad ,then I started to get a rash that was hives it would go away after using gold bond cream I stoped using the products 5 days ago. I still have some hives through out the day but they do go away. From what I have read the niacin in the product was the type that should not cause hives. I don’t want anything to do with this product. Thank you for all your work in the research.

    • Joe says

      Theresa, so sorry that happened to you. It might be the niacin or the itching could be due to an allergic reaction to something else in the product. I’m glad you are doing better now.

  30. says

    Although you furnish all the information it may be a bit misleading, especially because I don’t see where you have used the product., I am a Plexus Slim & Accelerator user and love it, and an Ambassador. I have lost weight, I don’t get the shakes like over the counter pills give you, and I don’t have the cravings like I used to.

    The Plexus Slim helps rid your intestinal tract of the bad bacteria that builds up in your system and replenishes the cells with more oxygen because it helps flush the dead cells from your system.

    I’m a medical professional and this has been the best product I have ever used, and I’ve tried just about all of them.

    One of the best parts about any of these products is there is a 60 day money back guarantee. You don’t get this if you buy from Amazon, though. So, if you don’t like the product and don’t have results, you can simply return it with no questions asked. It’s not for everyone, but it has helped tens of thousands achieve great results.

    • Joe says

      Susan I like to keep to the science for the most part because if I said it worked… or didn’t … how would you know for sure? I prefer to show you the evidence so you can make a more informed decision and let you decide for yourself.

      • Michael says

        I’d prefer that Mrs. Pohlman not advertise herself as a “Medical Professional” when she is in reality studying nursing. In addition, she seems to not have her products straight. It is the ProBio and BioCleanse that supposedly deals with intestinal tract issues.

  31. Kailey says

    This is the second day i have taken plexus accelerator and second day i feel like my heart is beating out of my chest. I will not take the accelerator again. Thank you for the information.

    • Michael says

      Kailey, this stuff is dangerous. To begin with, it’s a stimulant. Plexus has not been forthright in letting consumers know where this stuff is manufactured and they have “reformulated” this product. If people knew the damage that stimulants can do to their bodies, they might think twice. Athletes have died from taking stimulants – they only do one thing and that is increase your heart rate by chemical means. Stay away from this stuff.

  32. Kelly says

    I am from Canada and just finished a phone call with customer service. When I tried the old product 1 year ago, I lost 17 pounds in one month. Then I got the reformulation and ended up in ER with 180 BPM and a red burning flush on my body. I was pretty sure I was going to die.

    The rapid heart rate had me vomiting and I was told the ingredient niacin was responsible. I found some old bottles of the previous formulation and continued with those to lose 30 pounds. Then this new boost came out and I thought I would try that….High heart rate, the flush….just being on the drink, I have gained 20 pounds and crave carbs more than I ever have.

    So until they go back to the old formulation Plexus will not work for me. I am now at the biggest I have ever been and am so unhappy. I found something that worked and they changed it.

  33. Stephanie says

    I just took one Plexus Accelerator with breakfast. Within a half-hour my heart starting beating out of my chest. I felt nauseous and my hands got shaky and numb. My heartrate was over 150bpm. I am sitting trying to get my heartrate down. This stuff is scary.

    • Joe says

      Stephanie, please don’t take it again. It’s not worth it. I wish everybody would stop taking the accelerator and other stimulants. I wish Plexus would stop selling stimulants too. If plexus really was as great as people say, no other product should be needed.

      • Stephanie says

        I definitely won’t! I guess I was thinking it was very natural and safe. I called the nurseline at our local hospital and they wanted me to come in. I was feeling a bit better so I just stayed home and took a nap. It took over two hours for my heart rate to normalize. Now I just feel completely worn out. I will be returning the products. Lesson learned.

      • Michael says

        Joe, since Plexus “reformulated” Accelerator to the Plus version, have their been any subsequent changes to their ingredients?

        • Joe says

          Michael, Ive been meaning to update my review with the new formula and I apologize for not doing it sooner. Honestly I’m not sure about any other changes so if anyone has info please do list it. Ive actually gotten tried of trying to keep up with how they change things. They do it more than I’d like to see.

  34. Stacey Cooklin Montgomery says

    Fantastic article – very unbiased and informative. I do want to share that I have to be very careful about my caffeine intake while I’m taking the Accelerator as I get very jittery and nervous. Yesterday morning I took 2 of the pills in addition to a having small cup of coffee and I was really not feeling well by early afternoon. Lesson learned.

    • Joe says

      Stacey, thanks for saying that! Yes do be careful with caffeine if you are taking the Accelerator. your FB profile wasnt working when I clicked on it but do feel free to post it again with any other comments you have. Do keep me posted on your progress or if you have any questions :)

  35. Chris says

    My problem with the product is why would you pay 80 $ a month for something that you can do with just sisters changes that are at no cost ? How do people claim to get healthy and healed if they did nothing to change what they put into their bodies and causing their disease in the first place ? I will never believe any product that claims you can keep doing what you did and all the sudden get healthy and slim. It ‘a a lie , plain and simple.

    • Michael says

      Chris, your questions represent sane and logical thinking. The people who purchase this product are not on that same plane. Whether by desperation or ignorance, they simply disregard the fact that the human body cannot gain fitness via supplements. That requires exercise. A muscle will never develop, no matter how much protein you ingest, if you don’t put it under load.

      You will not become aerobically fit, no matter how many pills or powders you take, unless you engage in sustained exercise. Ingesting a stimulant and appetite suppressant is in no way gaining fitness or becoming “healthy”. In fact, you are exposing your body to potential health problems and in a roundabout way, becoming a drug addict.

      All of these testimonials you see claiming things are from those who have a financial interest in signing up people underneath them. This is no magical product – we don’t know where it is made and we don’t have assurances of its quality. Those who take it will bear the consequences of their actions down the line. Whether its the Higenamine or Yerba Mate that eventually causes a health issue, they will have regrets.

  36. says

    I’m on day 2 of taking PS and PS Accelerator+… I have bottomed out to the point of almost falling asleep at my desk both days around 2/2:30 in the afternoon. I’m going to continue my personal trial of the supplements to see if it lessens or goes away.

    • Joe says

      Abi, are you eating enough calories? I know when we go on a weight loss journey, we sometimes drastically cut back on calories. This may be why you are getting so tired. Not sure if that’s the issue but I thought I’d toss it out to you. Just my two cents but I really don’t recommend the Accelerator. Slow and steady weight loss is what’s important -not accelerated weight loss.

      Please read the comments if you already have not done so.

      • says

        Joe, thanks for the concern! I have been eating enough, yes. In fact, in the two weeks I have been using PS and its companions, I have gained six pounds. I do believe I’ll be returning the products this week.

  37. Betty says

    I’ve been taking Plexus Slim since the end of February 2015. No weight lost thru the end of May. I started taking the Accelerator at the end of May, starting out with just one then increased to 2. I don’t take them every morning, maybe 5 times a week. I have not noticed any adverse reactions to Accelerator. I originally started out taking the Bio Cleanse and eventually had to stop as I was having bowel movements every time I went to the bathroom and was just uncomfortable on the back side all the time. Turns out I was taking too many but I just have not had a desire to try them again. I’ve also been taking the ProBio5 at night, usually 2 but sometimes 3 pills.

    I’ve lost 6 pounds this month. This is after starting the Accelerator and trying the protein shakes, the P96. I love the smoothies in the morning. I can add my Plexus Slim to the smoothie along with a full serving of fruit. Unfortunately they are out of the P96 so I will have to switch back to drinking the Plexus Slim on it’s own. I can’t say I really like the taste, but I can tolerate it.

    Positive uses of Plexus: My blood sugar has decreased and I am beginning to crave healthy foods more. I am a stress eater and I have lots of stress in my life, hence I eat too much refined sugar. My sweet intake has finally gone down. This is supposed to be a benefit from Plexus, and for now I will give it the credit. (Note: I have had my blood sugar tested. I need to find my last blood results and compare them to this year’s, but I’m pretty sure the numbers went down, but I still need to verify. Last blood test they wanted to do more extensive testing since my blood sugar was high, this year it was a little high but not enough to warrant additional testing.)

    Negative uses of Plexus: Low energy. My job is labor intensive (tax accountant) so after April 15 I thought I was just low on energy due to the long hours and my body trying to recover. I was tired the entire month of May and into June. I am now only beginning to feel more normal. Supposedly the Plexus products are supposed to kill excess candida in my system and one side effect of the die off is fatigue. I plan to do more research on this but I am hoping if this is the case, I’m past the worst.

    I did sign up to be a Plexus ambassador but only for convenience of ordering. I have no intention of selling it to others unless I can give a personal testimony. After reading these reviews, I’ve decided to quit taking the Accelerator and ProBio5 after my supply has been depleted. There are some other products (Young Living) that I want to try to help with my energy and overall health that my friends have had positive personal experiences with.

    Plexus tells you to drink a lot of water. I’ve heard this habit alone can help you lose weight. I’ve not done very well with drinking the amount recommended and I wonder if that’s why I’ve not been losing weight.

    I really appreciate the review of the Plexus products here. Thanks for doing so much research Joe!

    • Joe says

      Hi Betty, I hope your blood tests come back as better. From what you said I would not be surprised if they are better. Are you dong any exercise – even walking – that can help with the stress (I can imagine the stress accountants go through!). Definitely drink water. Aim for about 1/2 of your body weight in oz per day spread out during the day. That might also help your stress eating too.

  38. Danielle says

    I took accelerator for one week . I do not recommend it . It is scary. The first time taking it I got dizzy and shaky , that was with taking 2 pills as it is recommended on the bottle. I opted to take just one pill in the morning with breakfast. This did not help much.

    I would still feel a little weird after taking them. I decided to try taking two pills again , and I got a very bad reaction. My heart was pounding really hard, as if I had been running . My heart continued like this for about 10 minutes. I tried my best to remain calm , I ate some sugary fruit , and drank water.

    Eventually my heart went back to normal rate. If these pills can cause your heart rate to go up like that unexpectedly , that is dangerous.

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